PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 25632967-0 2015 Lycopene-rich tomato oleoresin modulates plasma adiponectin concentration and mRNA levels of adiponectin, SIRT1, and FoxO1 in adipose tissue of obese rats. Lycopene 0-8 sirtuin 1 Rattus norvegicus 106-111 25632967-1 2015 AIM: To investigate whether lycopene can modulate adiponectin levels and SIRT1 and FoxO1 gene expression in the adipose tissue of diet-induced obese rats. Lycopene 28-36 sirtuin 1 Rattus norvegicus 73-78 25632967-7 2015 In addition, the lycopene supplementation upregulated mRNA expressions of SIRT1, FoxO1, and FAT/CD36 but downregulated PPARgamma in adipose tissue of obese rats. Lycopene 17-25 sirtuin 1 Rattus norvegicus 74-79 32712090-3 2020 Compared with expression in the sham group, mTOR, pS6, p4EBP, GFAP, and Iba-1 decreased and SIRT1 increased in the lycopene group (P < 0.01). Lycopene 115-123 sirtuin 1 Rattus norvegicus 92-97 32712090-6 2020 Intrathecal injection of 3-MA (a mTOR agonist) or EX-527 (an inhibitor of Sirt1) partially antagonized lycopene-induced analgesia. Lycopene 103-111 sirtuin 1 Rattus norvegicus 74-79 32712090-9 2020 The present data indicated that the SIRT1/mTOR pathway changed in the spinal dorsal horn of BIP rats; Lycopene alleviated the pain sensitization of BIP rats by regulating the SIRT1/mTOR pathway and glial activation in the spinal dorsal horn. Lycopene 102-110 sirtuin 1 Rattus norvegicus 36-41 32712090-9 2020 The present data indicated that the SIRT1/mTOR pathway changed in the spinal dorsal horn of BIP rats; Lycopene alleviated the pain sensitization of BIP rats by regulating the SIRT1/mTOR pathway and glial activation in the spinal dorsal horn. Lycopene 102-110 sirtuin 1 Rattus norvegicus 175-180