PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
30719147-9	2019	Moreover, JNK inhibitor (SP600125) and MEK inhibitor (U0126) treatment abolished the increase in phosphorylated MTOR and ribosomal protein S6 as well as the increase in ZO-1 and the decrease in claudin-1 in lycopene-treated COLO-16 cells.	Lycopene	207-215	mitogen-activated protein kinase 8	Homo sapiens	10-13	
17950366-7	2007	PDGF-BB-induced phosphorylation of PDGF receptor beta (PDGFR-beta), extracellular signal-regulated kinase 1/2 (ERK1/2), p38, and c-Jun N-terminal kinase (JNK) was attenuated by lycopene in a concentration-dependent manner, whereas the total expression of each protein was not affected.	Lycopene	177-185	mitogen-activated protein kinase 8	Homo sapiens	129-152	
30719147-11	2019	In conclusion, lycopene upregulates ZO-1 expression and downregulates claudin-1 expression through the activation of ERK, JNK and MTORC1 as well as the inhibition of autophagy in human cSCC cells.	Lycopene	15-23	mitogen-activated protein kinase 8	Homo sapiens	122-125	
28386381-10	2017	The protein expressions of NF-kappaB and JNK were decreased significantly according to lycopene concertation (P < 0.05).	Lycopene	87-95	mitogen-activated protein kinase 8	Homo sapiens	41-44	
28386381-11	2017	CONCLUSIONS: Lycopene restrains NF-kappaB and JNK activation, which causes inflammation, and suppresses the expression of TNF-alpha, IL-1beta, IL-6, COX-2, and iNOS in SW480 human colorectal cancer cells.	Lycopene	13-21	mitogen-activated protein kinase 8	Homo sapiens	46-49	
21625550-10	2011	Lycopene further inhibited CSE-induced phosphorylation of the redox-sensitive ERK1/2, JNK and p38 MAPKs.	Lycopene	0-8	mitogen-activated protein kinase 8	Homo sapiens	86-89	
22648619-6	2012	It appeared that the LPS-activation of both JNK and NF-kappaB signaling pathways was modulated by lycopene.	Lycopene	98-106	mitogen-activated protein kinase 8	Homo sapiens	44-47