PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 21923160-10 2011 The molecular mechanisms of lycopene were in part through decreases in nuclear levels of AP-1 and beta-catenin proteins. Lycopene 28-36 catenin beta 1 Homo sapiens 98-110 31741457-0 2019 Lycopene induces apoptosis by inhibiting nuclear translocation of beta-catenin in gastric cancer cells. Lycopene 0-8 catenin beta 1 Homo sapiens 66-78 31741457-9 2019 Lycopene induces apoptosis by reducing ROS levels and suppressing beta-catenin-c-myc/cyclin D1 axis. Lycopene 0-8 catenin beta 1 Homo sapiens 66-78 31741457-10 2019 Thus, lycopene induces apoptosis of gastric cancer cells by disrupting nuclear translocation of beta-catenin and expression of key cell survival genes. Lycopene 6-14 catenin beta 1 Homo sapiens 96-108 18283040-11 2008 In this study, lycopene, in dietary concentrations, reversed DHT effects of 6S cells on NPE cell death, decreased 6S cell IGF-I production by reducing AR and beta-catenin nuclear localization and inhibited IGF-I-stimulated NPE and PREC growth, perhaps by attenuating IGF-I"s effects on serine phosphorylation of Akt and GSK3beta and tyrosine phosphorylation of GSK3. Lycopene 15-23 catenin beta 1 Homo sapiens 158-170 18537129-8 2008 Lycopene treatment suppressed Akt activation and non-phosphorylated beta-catenin protein level in human colon cancer cells. Lycopene 0-8 catenin beta 1 Homo sapiens 68-80 18537129-9 2008 Immunocytochemical results indicated that lycopene increased the phosphorylated form of beta-catenin proteins. Lycopene 42-50 catenin beta 1 Homo sapiens 88-100 20155615-7 2009 Lycopene modulates several of the aforementioned pathways, providing a promising rationale for prostate cancer risk reduction by lycopene: In many experimental setups, lycopene reduced inflammatory signals, prevented oxidative DNA damage, modulated the expression or activity of IGF axis members, of Wnt/beta-catenin and androgen signalling, and enhanced gap junctional communication. Lycopene 0-8 catenin beta 1 Homo sapiens 304-316 20155615-7 2009 Lycopene modulates several of the aforementioned pathways, providing a promising rationale for prostate cancer risk reduction by lycopene: In many experimental setups, lycopene reduced inflammatory signals, prevented oxidative DNA damage, modulated the expression or activity of IGF axis members, of Wnt/beta-catenin and androgen signalling, and enhanced gap junctional communication. Lycopene 168-176 catenin beta 1 Homo sapiens 304-316