PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 21672580-3 2011 This review focuses on the role of carotenoids like retinoic acid (RA), all trans retinoic acid (ATRA), lycopene and beta-carotene in prevention of AD symptoms primarily through inhibition of amyloid beta (Abeta) formation, deposition and fibril formation either by reducing the levels of p35 or inhibiting corresponding enzymes. Lycopene 104-112 amyloid beta precursor protein Homo sapiens 192-204 26453763-5 2015 Lycopene treatment reduced Abeta1-42 secretion in SH-SY5Y cells overexpressing the Swedish mutant form of human beta-amyloid precursor protein (APPsw). Lycopene 0-8 amyloid beta precursor protein Homo sapiens 112-142 26453763-6 2015 Next, we found lycopene can down-regulate expression level of beta-amyloid precursor protein(APP) in APPsw cells. Lycopene 15-23 amyloid beta precursor protein Homo sapiens 62-92 21672580-3 2011 This review focuses on the role of carotenoids like retinoic acid (RA), all trans retinoic acid (ATRA), lycopene and beta-carotene in prevention of AD symptoms primarily through inhibition of amyloid beta (Abeta) formation, deposition and fibril formation either by reducing the levels of p35 or inhibiting corresponding enzymes. Lycopene 104-112 amyloid beta precursor protein Homo sapiens 206-211