PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
34856476-6	2022	RESULTS: Different classes of phytopigments such as carotenoids, xanthophylls, flavonoids, anthocyanins, anthraquinones alleviate major CVDs (e.g., cardiac hypertrophy, atherosclerosis, hypertension, cardiotoxicities) via acting on signaling pathways related to AMPK, NF-kappaB, NRF2, PPARs, AKT, TLRs, MAPK, JAK/STAT, NLRP3, TNF-alpha, and RA.	Carotenoids	52-63	tumor necrosis factor	Homo sapiens	326-335	
32410856-6	2020	In ECs and monocytes, three carotenoids, i.e., beta-cryptoxanthin, lutein, and lycopene, suppressed the fructose-induced expression of chemokines MCP-1, M-CSF, and CXCL-10 and inflammatory cytokines TNF-alpha and IL-1beta, with CXCL-10 being the most repressed inflammatory mediator.	Carotenoids	28-39	tumor necrosis factor	Homo sapiens	199-208	
29551222-0	2018	A diet high in carotenoid-rich vegetables and fruits favorably impacts inflammation status by increasing plasma concentrations of IFN-alpha2 and decreasing MIP-1beta and TNF-alpha in healthy individuals during a controlled feeding trial.	Carotenoids	15-25	tumor necrosis factor	Homo sapiens	170-179	
29551222-8	2018	Of the inflammatory markers measured, we found increased plasma concentrations of interferon alpha-2 (P = .003) and decreased macrophage inflammatory protein-1beta (P = .027) and tumor necrosis factor-alpha (P = .012) after consumption of the carotenoid-rich diet.	Carotenoids	243-253	tumor necrosis factor	Homo sapiens	179-206	
29495330-1	2018	(1) Background: Carotenoids may be inversely associated with inflammatory markers (i.e., TNF-alpha, IL-6, IL-1beta).	Carotenoids	16-27	tumor necrosis factor	Homo sapiens	89-98	
29495330-6	2018	(3) Results: Generally, serum individual and total carotenoids were significantly and inversely associated with retinol-adjusted RBP4, RBP4, hsCRP, MCP1, and TNF-alpha levels.	Carotenoids	51-62	tumor necrosis factor	Homo sapiens	158-167	
29495330-9	2018	Among the individual carotenoids, those with the most predominant association were lutein-zeaxanthin and total carotenoids for retinol-adjusted RBP4 and RBP4, alpha- and beta-carotene for hsCRP, and alpha-carotene for MCP1 and TNF-alpha.	Carotenoids	21-32	tumor necrosis factor	Homo sapiens	227-236	
29495330-11	2018	(4) Conclusions: Serum carotenoids were inversely associated with RBP4, hsCRP, MCP1 and TNF-alpha among middle-aged and elderly Chinese adults.	Carotenoids	23-34	tumor necrosis factor	Homo sapiens	88-97	
24830761-9	2014	Significant inverse associations were reported between IL-6, TNF-alpha, and IFN-gamma levels and quartiles of total reported carotenoid intake (P = .006, P = .04, and P = .04, respectively).	Carotenoids	125-135	tumor necrosis factor	Homo sapiens	61-70