PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
16563717-0	2006	Carotenoids enhance phosphorylation of Akt and suppress tissue factor activity in human endothelial cells.	Carotenoids	0-11	AKT serine/threonine kinase 1	Homo sapiens	39-42	
23613227-6	2013	Further, those two marine algal carotenoids down-regulate the phosphorylation of FGF-2-mediated intracellular signaling proteins such as ERK1/2 and Akt.	Carotenoids	32-43	AKT serine/threonine kinase 1	Homo sapiens	148-151	
34856476-6	2022	RESULTS: Different classes of phytopigments such as carotenoids, xanthophylls, flavonoids, anthocyanins, anthraquinones alleviate major CVDs (e.g., cardiac hypertrophy, atherosclerosis, hypertension, cardiotoxicities) via acting on signaling pathways related to AMPK, NF-kappaB, NRF2, PPARs, AKT, TLRs, MAPK, JAK/STAT, NLRP3, TNF-alpha, and RA.	Carotenoids	52-63	AKT serine/threonine kinase 1	Homo sapiens	292-295	
16563717-6	2006	Our study also demonstrated that addition of Akt-specific inhibitor reversed the inhibitory effect of carotenoids on tissue factor activity, indicating that carotenoids enhanced phosphorylation of Akt and suppressed tissue factor activity in endothelial cells by this mechanism.	Carotenoids	102-113	AKT serine/threonine kinase 1	Homo sapiens	45-48	
16563717-6	2006	Our study also demonstrated that addition of Akt-specific inhibitor reversed the inhibitory effect of carotenoids on tissue factor activity, indicating that carotenoids enhanced phosphorylation of Akt and suppressed tissue factor activity in endothelial cells by this mechanism.	Carotenoids	102-113	AKT serine/threonine kinase 1	Homo sapiens	197-200	
16563717-6	2006	Our study also demonstrated that addition of Akt-specific inhibitor reversed the inhibitory effect of carotenoids on tissue factor activity, indicating that carotenoids enhanced phosphorylation of Akt and suppressed tissue factor activity in endothelial cells by this mechanism.	Carotenoids	157-168	AKT serine/threonine kinase 1	Homo sapiens	45-48	
16563717-6	2006	Our study also demonstrated that addition of Akt-specific inhibitor reversed the inhibitory effect of carotenoids on tissue factor activity, indicating that carotenoids enhanced phosphorylation of Akt and suppressed tissue factor activity in endothelial cells by this mechanism.	Carotenoids	157-168	AKT serine/threonine kinase 1	Homo sapiens	197-200