PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 30908741-8 2019 Total carotenoids positively correlated with per cent-predicted FEV1 and inversely correlated with insulin resistance among obese asthmatics only. Carotenoids 6-17 insulin Homo sapiens 99-106 33345665-4 2021 In children, two double-blind randomised placebo-controlled studies describing the effects of diet vs. mixed carotenoid supplementation on insulin resistance, adipokines and the rate of accrual of subcutaneous abdominal fat, implicate supplementation of these compounds to achieve targetable levels may be useful in the management of obesity accrual in this population. Carotenoids 109-119 insulin Homo sapiens 139-146 33345665-5 2021 We will discuss the role of carotenoids and their conversion products (retinoids) in adipogenesis, lipolysis, insulin resistance and the pathophysiology of the metabolic syndrome and review the animal studies, which help support these findings. Carotenoids 28-39 insulin Homo sapiens 110-117 31504714-0 2020 Obesity and Insulin Resistance Are Inversely Associated with Serum and Adipose Tissue Carotenoid Concentrations in Adults. Carotenoids 86-96 insulin Homo sapiens 12-19 31504714-1 2020 BACKGROUND: Low tissue concentrations of carotenoids have been suggested to contribute to insulin resistance in obesity. Carotenoids 41-52 insulin Homo sapiens 90-97 31504714-11 2020 CONCLUSIONS: Multiple serum and adipose tissue carotenoids are associated with favorable metabolic traits, including insulin sensitivity in liver and adipose tissue in humans. Carotenoids 47-58 insulin Homo sapiens 117-124 24906472-1 2015 PURPOSE: Many epidemiological studies find an inverse correlation between carotenoids intake or carotenoids plasma concentrations and body mass index (BMI), insulin resistance or metabolic syndrome in the general population. Carotenoids 74-85 insulin Homo sapiens 157-164 24906472-1 2015 PURPOSE: Many epidemiological studies find an inverse correlation between carotenoids intake or carotenoids plasma concentrations and body mass index (BMI), insulin resistance or metabolic syndrome in the general population. Carotenoids 96-107 insulin Homo sapiens 157-164 23936766-0 2013 Serum Retinol and Carotenoids in Association with Biomarkers of Insulin Resistance among Premenopausal Women. Carotenoids 18-29 insulin Homo sapiens 64-71 25660385-6 2015 Further properties of carotenoids leading to a potential reduction of cardiovascular risk are represented by lowering of blood pressure, reduction of pro-inflammatory cytokines and markers of inflammation (such as C-reactive protein), and improvement of insulin sensitivity in muscle, liver, and adipose tissues. Carotenoids 22-33 insulin Homo sapiens 254-261 10966898-0 2000 Relation between insulin resistance and plasma concentrations of lipid hydroperoxides, carotenoids, and tocopherols. Carotenoids 87-98 insulin Homo sapiens 17-24 16597706-0 2006 Associations of serum carotenoid concentrations with the development of diabetes and with insulin concentration: interaction with smoking: the Coronary Artery Risk Development in Young Adults (CARDIA) Study. Carotenoids 22-32 insulin Homo sapiens 90-97 16597706-7 2006 Similarly, year 15 insulin and insulin resistance values, adjusted for baseline levels, were inversely related to sum of carotenoids only in nonsmokers (per SD increase in insulin level, slope = -0.46 (p = 0.03); per SD increase in insulin resistance, slope = -0.14 (p = 0.01)). Carotenoids 121-132 insulin Homo sapiens 19-26 16597706-7 2006 Similarly, year 15 insulin and insulin resistance values, adjusted for baseline levels, were inversely related to sum of carotenoids only in nonsmokers (per SD increase in insulin level, slope = -0.46 (p = 0.03); per SD increase in insulin resistance, slope = -0.14 (p = 0.01)). Carotenoids 121-132 insulin Homo sapiens 31-38 16597706-7 2006 Similarly, year 15 insulin and insulin resistance values, adjusted for baseline levels, were inversely related to sum of carotenoids only in nonsmokers (per SD increase in insulin level, slope = -0.46 (p = 0.03); per SD increase in insulin resistance, slope = -0.14 (p = 0.01)). Carotenoids 121-132 insulin Homo sapiens 31-38 16597706-8 2006 In CARDIA, higher serum carotenoid concentrations are associated with lower risk of diabetes and insulin resistance in nonsmokers but not in smokers. Carotenoids 24-34 insulin Homo sapiens 97-104 16155284-6 2005 RESULTS: Mean 2-h postload plasma glucose and fasting insulin concentrations decreased significantly with increasing quintiles of the 5 serum carotenoids--alpha-carotene, beta-carotene, beta-cryptoxanthin, lutein/zeaxanthin, and lycopene. Carotenoids 142-153 insulin Homo sapiens 54-61 9921962-4 1999 All serum carotenoids were inversely related to fasting serum insulin after adjustment for confounders (p < 0.05 for each carotenoid). Carotenoids 10-21 insulin Homo sapiens 62-69 9921962-4 1999 All serum carotenoids were inversely related to fasting serum insulin after adjustment for confounders (p < 0.05 for each carotenoid). Carotenoids 10-20 insulin Homo sapiens 62-69 9921962-5 1999 If confirmed, these data suggest new opportunities for research that include exploring a possible role for carotenoids in the pathogenesis of insulin resistance and diabetes. Carotenoids 107-118 insulin Homo sapiens 142-149