PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 20678906-10 2012 Both crude and lipid-adjusted carotenoids were inversely correlated with CRP and IL-6 in plasma but the change in carotenoid status during simvastatin therapy was not specifically related to any changes in inflammatory markers. Carotenoids 30-41 interleukin 6 Homo sapiens 81-85 20678906-10 2012 Both crude and lipid-adjusted carotenoids were inversely correlated with CRP and IL-6 in plasma but the change in carotenoid status during simvastatin therapy was not specifically related to any changes in inflammatory markers. Carotenoids 30-40 interleukin 6 Homo sapiens 81-85 33808148-4 2021 Indeed, it was found in keratinocytes that carotenoids and polyphenols inhibit UVB-induced NFkappaB activity and release of cytokine IL-6. Carotenoids 43-54 interleukin 6 Homo sapiens 133-137 20580698-6 2010 In women, there were significant negative associations between serum carotenoids concentrations and serum interleukin-6 (IL-6) concentrations. Carotenoids 69-80 interleukin 6 Homo sapiens 106-119 20580698-6 2010 In women, there were significant negative associations between serum carotenoids concentrations and serum interleukin-6 (IL-6) concentrations. Carotenoids 69-80 interleukin 6 Homo sapiens 121-125 20077945-8 2009 CRP, IL-6 and conjugated dienes correlated with BMI, while IL-6 and conjugated dienes correlated inversely with carotenoids (P < 0.05). Carotenoids 112-123 interleukin 6 Homo sapiens 59-63 17196927-3 2007 Carotenoids quench free radicals, reduce damage from reactive oxygen species, and appear to modulate redox-sensitive transcription factors such as NF-kappaB that are involved in the upregulation of IL-6 and other proinflammatory cytokines. Carotenoids 0-11 interleukin 6 Homo sapiens 198-202 16306311-6 2006 Participants with the highest serum levels of alpha-carotene, total carotenoids, and selenium were significantly less likely to be in the highest tertile of serum IL-6 at baseline (p < 0.0001). Carotenoids 68-79 interleukin 6 Homo sapiens 163-167 16306311-7 2006 Those with the lowest levels of alpha- and beta-carotene, lutein/zeaxanthin, and total carotenoids were significantly more likely to have increasing IL-6 levels over a period of 2 years. Carotenoids 87-98 interleukin 6 Homo sapiens 149-153 28527371-3 2017 Here, we first assessed relationships between interleukin (IL)-6 and individual carotenoids in plasma from CAD patients. Carotenoids 80-91 interleukin 6 Homo sapiens 46-64 30126098-8 2018 Multiple linear regression, controlling for age and body mass index (BMI), demonstrated an inverse association between serum carotenoid concentrations and pro-inflammatory sTNFR-II (beta = 0.404, p = 0.005) and IL-6 concentrations (beta = -0.35, p = 0.001), but not IL-1ra or CRP. Carotenoids 125-135 interleukin 6 Homo sapiens 211-215 29495330-1 2018 (1) Background: Carotenoids may be inversely associated with inflammatory markers (i.e., TNF-alpha, IL-6, IL-1beta). Carotenoids 16-27 interleukin 6 Homo sapiens 100-104 24830761-9 2014 Significant inverse associations were reported between IL-6, TNF-alpha, and IFN-gamma levels and quartiles of total reported carotenoid intake (P = .006, P = .04, and P = .04, respectively). Carotenoids 125-135 interleukin 6 Homo sapiens 55-59 26923510-11 2016 IL-6 was a significant mediator of the association between fruits with low carotenoid content and depression in women. Carotenoids 75-85 interleukin 6 Homo sapiens 0-4 25313576-11 2014 Inflammatory biomarker concentrations decreased markedly across the quintiles of carotenoid component score (P< 0 001 for hs-CRP and IL-6, and P= 0 016 for E-selectin; ANCOVA). Carotenoids 81-91 interleukin 6 Homo sapiens 136-140 22486775-7 2012 RESULTS: Lower plasma levels of total and single carotenoids were associated with lower dietary intake of carotenoids, older age, male sex, lower physical activity, higher alcohol consumption, higher body mass index (BMI), higher systolic and diastolic blood pressures, lower levels of total cholesterol and HDL cholesterol and higher levels of CRP, IL-6 and MMP-9. Carotenoids 49-60 interleukin 6 Homo sapiens 350-354 22365613-2 2012 Vitamin E and the carotenoids are two classes of dietary antioxidants with profound anti-inflammatory effects, and the goal of this study was to assess whether higher post-fracture concentrations of these antioxidants were associated with lower levels of interleukin 6 (IL-6) and the soluble receptor for tumor necrosis factor-alpha (sTNF-alphaR1), two common markers of inflammation. Carotenoids 18-29 interleukin 6 Homo sapiens 255-268 22486775-8 2012 After multivariate adjustments, plasma levels of total carotenoids and provitamin A carotenoids (beta-cryptoxanthine, alpha-carotene and beta-carotene) remained independently associated with sex, dietary intake of carotenoids, BMI, HDL cholesterol and MMP-9, whilst associations with CRP and IL-6 were not maintained. Carotenoids 55-66 interleukin 6 Homo sapiens 292-296 22226662-9 2012 Also, changes in plasma total carotenoid and lycopene concentration were inversely correlated with the changes in IL-6 production in LPS-activated PBMCs. Carotenoids 30-40 interleukin 6 Homo sapiens 114-118