PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
23166730-6	2012	On the other hand, providing an antioxidant supplement (astaxanthin, a polar carotenoid) to humans was found to decrease RBC Abeta as well as oxidative stress marker levels.	Carotenoids	77-87	amyloid beta precursor protein	Homo sapiens	125-130	
21459092-2	2011	In this study, we conducted in vitro and in vivo studies, which provide evidence that Abeta induces oxidative injury to RBC by binding to them, causing RBC phospholipid peroxidation and diminishing RBC endogenous carotenoids, especially xanthophylls.	Carotenoids	213-224	amyloid beta precursor protein	Homo sapiens	86-91	
21672580-3	2011	This review focuses on the role of carotenoids like retinoic acid (RA), all trans retinoic acid (ATRA), lycopene and beta-carotene in prevention of AD symptoms primarily through inhibition of amyloid beta (Abeta) formation, deposition and fibril formation either by reducing the levels of p35 or inhibiting corresponding enzymes.	Carotenoids	35-46	amyloid beta precursor protein	Homo sapiens	192-204	
21672580-3	2011	This review focuses on the role of carotenoids like retinoic acid (RA), all trans retinoic acid (ATRA), lycopene and beta-carotene in prevention of AD symptoms primarily through inhibition of amyloid beta (Abeta) formation, deposition and fibril formation either by reducing the levels of p35 or inhibiting corresponding enzymes.	Carotenoids	35-46	amyloid beta precursor protein	Homo sapiens	206-211	
34356811-14	2021	A beta-carotene synthase gene, with a different domain organization compared to the gene in other thraustochytrids, explained the carotenoid profile of RT2316-16.	Carotenoids	130-140	amyloid beta precursor protein	Homo sapiens	0-6	
28553090-7	2017	Molecular modeling analysis revealed that the evaluated carotenoids might follow two mechanisms for inhibiting Abeta aggregation: by preventing the formation of the fibril and through disruption of the Abeta aggregates.	Carotenoids	56-67	amyloid beta precursor protein	Homo sapiens	111-116	
31703296-6	2019	Our computational structure-based drug design analysis and molecular docking simulation revealed important interactions between carotenoids and Abeta via hydrogen bonding and van der Waals interactions, and shows that carotenoids are powerful anti-amyloidogenic molecules with a potential role in preventing AD, especially since most of them can cross the blood-brain barrier and are considered nutraceutical compounds.	Carotenoids	128-139	amyloid beta precursor protein	Homo sapiens	144-149	
31703296-6	2019	Our computational structure-based drug design analysis and molecular docking simulation revealed important interactions between carotenoids and Abeta via hydrogen bonding and van der Waals interactions, and shows that carotenoids are powerful anti-amyloidogenic molecules with a potential role in preventing AD, especially since most of them can cross the blood-brain barrier and are considered nutraceutical compounds.	Carotenoids	218-229	amyloid beta precursor protein	Homo sapiens	144-149