PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
19486882-0	2009	Calcium enhances the proteolytic activity of BACE1: An in vitro biophysical and biochemical characterization of the BACE1-calcium interaction.	Calcium	0-7	beta-secretase 1	Homo sapiens	45-50	
19486882-0	2009	Calcium enhances the proteolytic activity of BACE1: An in vitro biophysical and biochemical characterization of the BACE1-calcium interaction.	Calcium	0-7	beta-secretase 1	Homo sapiens	116-121	
19486882-0	2009	Calcium enhances the proteolytic activity of BACE1: An in vitro biophysical and biochemical characterization of the BACE1-calcium interaction.	Calcium	122-129	beta-secretase 1	Homo sapiens	45-50	
19486882-0	2009	Calcium enhances the proteolytic activity of BACE1: An in vitro biophysical and biochemical characterization of the BACE1-calcium interaction.	Calcium	122-129	beta-secretase 1	Homo sapiens	116-121	
32704090-6	2021	We found that urolithin A-lowered mitochondrial calcium influx significantly alleviated high glucose-induced mtROS accumulation and expression of amyloid beta (Abeta)-producing enzymes, such as amyloid precursor protein (APP) and beta-secretase-1 (BACE1), as well as Abeta production.	Calcium	48-55	beta-secretase 1	Homo sapiens	230-246	
18081741-0	2008	Disrupted intracellular calcium regulates BACE1 gene expression via nuclear factor of activated T cells 1 (NFAT 1) signaling.	Calcium	24-31	beta-secretase 1	Homo sapiens	42-47	
18081741-3	2008	BACE1 expression was stimulated by a calcium ionophore in primary cortical cultures, and by SH-SY5Y neuroblastoma cells, which was both blocked by pretreatment with either cyclosporin A, an inhibitor of calcineurin, or ethyleneglycotetraacetic acid, a calcium chelator.	Calcium	37-44	beta-secretase 1	Homo sapiens	0-5	
18081741-3	2008	BACE1 expression was stimulated by a calcium ionophore in primary cortical cultures, and by SH-SY5Y neuroblastoma cells, which was both blocked by pretreatment with either cyclosporin A, an inhibitor of calcineurin, or ethyleneglycotetraacetic acid, a calcium chelator.	Calcium	252-259	beta-secretase 1	Homo sapiens	0-5	
31327057-2	2019	Specifically, the interaction of magnesium di-cation with the previously reported calcium binding sites (ASP2, ASP117, ASP159, GLU114, GLU119, GLU120, and VAL226) was investigated to identify similarities and differences between them.	Calcium	82-89	beta-secretase 1	Homo sapiens	105-109	
30466042-9	2018	Besides, we identified novel calcium biding sites: ASP2, ASP117, ASP159, GLU114, GLU119, GLU120 and VAL226.	Calcium	29-36	beta-secretase 1	Homo sapiens	51-55