PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
33543729-8	2021	In men, serum calcium and phosphate levels were highest in the youngest age group compared to age groups 18-44 and >=45 years.	Calcium	14-21	renin binding protein	Homo sapiens	72-75	
33829643-0	2021	Age-related calcium dysregulation linked with tau pathology and impaired cognition in non-human primates.	Calcium	12-19	renin binding protein	Homo sapiens	0-3	
33829643-6	2021	Age-related reductions in the calcium-binding protein, calbindin, and in phosphodiesterase PDE4D were seen within dlPFC pyramidal cell dendrites.	Calcium	30-37	renin binding protein	Homo sapiens	0-3	
33543729-0	2021	Age-dependent sex differences in calcium and phosphate homeostasis.	Calcium	33-40	renin binding protein	Homo sapiens	0-3	
33543729-9	2021	In women, serum calcium levels were also significantly higher in the age group 1-17 and the age group >=45 years compared to the 18-44 years age group.	Calcium	16-23	renin binding protein	Homo sapiens	69-72	
33543729-9	2021	In women, serum calcium levels were also significantly higher in the age group 1-17 and the age group >=45 years compared to the 18-44 years age group.	Calcium	16-23	renin binding protein	Homo sapiens	92-95	
33543729-9	2021	In women, serum calcium levels were also significantly higher in the age group 1-17 and the age group >=45 years compared to the 18-44 years age group.	Calcium	16-23	renin binding protein	Homo sapiens	92-95	
33543729-11	2021	CONCLUSION: There are age dependent sex differences in serum calcium and phosphate.	Calcium	61-68	renin binding protein	Homo sapiens	22-25	
33543729-12	2021	Furthermore, we found differences in serum calcium and phosphate between different age groups.	Calcium	43-50	renin binding protein	Homo sapiens	83-86	
33582830-5	2021	We identified significant interactions between age and creatinine clearance in predicting 24-h urine pH, calcium, and citrate.	Calcium	105-112	renin binding protein	Homo sapiens	47-50	
33196098-10	2020	Pathway enrichment revealed that the calcium signaling pathway was significantly enriched and the MAPK signaling pathway, cAMP signaling pathway, cancer and vascular smooth muscle contraction pathways, cGMP-PKG signaling pathway, and AGE-RAGE signaling pathway were closely associated with XLW intervention for UFs.	Calcium	37-44	renin binding protein	Homo sapiens	234-237	
31250032-2	2019	The advanced glycation end product (AGE) and receptor for AGE (RAGE) signaling pathway regulates the pathogenesis of CVDs, through its effects on arterial stiffness, atherosclerosis, mitochondrial dysfunction, oxidative stress, calcium homeostasis, and cytoskeletal function.	Calcium	228-235	renin binding protein	Homo sapiens	36-39	
32276008-11	2020	Pathway enrichment analysis of target proteins indicated that Neuroactive ligand-receptor interaction, Calcium signaling pathway, Serotonergic synapse, cAMP signaling pathway and Gap junction were the common primary pathways regulated by both Yixin Ningshen Tablet and anti-depressant drugs, and MAPK, Relaxin, AGE-RAGE, Estrogen, HIF-1, Jak-STAT signaling pathway, Endocrine resistance, Arachidonic acid metabolism and Regulation of actin cytoskeleton were the specifically main pathways regulated by Yixin Ningshen tablet for the treatment of depression.	Calcium	103-110	renin binding protein	Homo sapiens	311-314	
31712319-0	2020	Inhibition of Mitochondrial Calcium Overload by SIRT3 Prevents Obesity- or Age-Related Whitening of Brown Adipose Tissue.	Calcium	28-35	renin binding protein	Homo sapiens	75-78	
33281988-11	2020	Identification of calcium-regulated developmental disparities in shear-mediated platelet function may provide novel targets for age-specific antiplatelet therapy.	Calcium	18-25	renin binding protein	Homo sapiens	128-131	
31250032-2	2019	The advanced glycation end product (AGE) and receptor for AGE (RAGE) signaling pathway regulates the pathogenesis of CVDs, through its effects on arterial stiffness, atherosclerosis, mitochondrial dysfunction, oxidative stress, calcium homeostasis, and cytoskeletal function.	Calcium	228-235	renin binding protein	Homo sapiens	58-61	
34403092-0	2021	Downregulation of Cav3.1 T-type Calcium Channel Expression in Age-related Hearing Loss Model.	Calcium	32-39	renin binding protein	Homo sapiens	62-65	
22662249-4	2012	Exogenous AGE-albumin upregulates the receptor protein for AGE (RAGE) and augments calcium influx, leading to apoptosis of human primary neurons.	Calcium	83-90	renin binding protein	Homo sapiens	10-13	
21874328-0	2011	Age-related loss of calcium buffering and selective neuronal vulnerability in Alzheimer"s disease.	Calcium	20-27	renin binding protein	Homo sapiens	0-3	
9666048-3	1998	Results from age- and OS-sensitive tests are given; these results indicate that one of the major sites of action of OS is the membranes, especially if compromised by high amounts of sphingomyelin, and one of the major effects of OS is to further alter the calcium disregulation in aging.	Calcium	256-263	renin binding protein	Homo sapiens	13-16