PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
35157798-6	2022	Calcium drives the N-terminal of the Spike fusion domain to fully cross the host plasma membrane.	Calcium	0-7	surface glycoprotein	Severe acute respiratory syndrome coronavirus 2	37-42	
34410575-4	2021	The results show that after the EF-hand domain of S protein bound to calcium ions, S2 protein had CaMKII protein activities.	Calcium	69-76	surface glycoprotein	Severe acute respiratory syndrome coronavirus 2	50-51	
35397208-3	2022	Here, we reconstituted an in vitro pseudovirus-liposome fusion reaction and report that SARS-CoV-2 wild-type spike is a dynamic Ca2+ sensor, and D614G mutation enhances dynamic calcium sensitivity of spike protein for facilitating membrane fusion.	Calcium	177-184	surface glycoprotein	Severe acute respiratory syndrome coronavirus 2	109-114	
35397208-3	2022	Here, we reconstituted an in vitro pseudovirus-liposome fusion reaction and report that SARS-CoV-2 wild-type spike is a dynamic Ca2+ sensor, and D614G mutation enhances dynamic calcium sensitivity of spike protein for facilitating membrane fusion.	Calcium	177-184	surface glycoprotein	Severe acute respiratory syndrome coronavirus 2	200-205	
35397208-4	2022	This dynamic calcium sensitivity for fusion is found to be higher in Alpha and Beta variants and highest in Delta spike variant.	Calcium	13-20	surface glycoprotein	Severe acute respiratory syndrome coronavirus 2	114-119	
33827113-8	2021	One of the most effective molecules was Niclosamide, which markedly blunted calcium oscillations and membrane conductances in Spike-expressing cells by suppressing the activity of TMEM16F/Anoctamin6, a calcium-activated ion channel and scramblase responsible for phosphatidylserine exposure on the cell surface.	Calcium	76-83	surface glycoprotein	Severe acute respiratory syndrome coronavirus 2	126-131	
33552855-3	2021	This CID tool, evolved from an anti-caffeine nanobody via cell-based high-throughput screening, permits caffeine-inducible gating of calcium channels, tumor killing via necroptosis, growth factors-independent activation of tyrosine receptor kinase signaling, and enhancement of nanobody-mediated antigen recognition for the severe acute respiratory distress coronavirus 2 (SARS-CoV-2) spike protein.	Calcium	133-140	surface glycoprotein	Severe acute respiratory syndrome coronavirus 2	385-390	
33784482-10	2021	These results conclusively demonstrate that the calcium independent rfhSP-D mediated inhibition of binding between the receptor binding domain of the S1 subunit of the SARS-CoV-2 spike protein and human ACE-2, its host cell receptor, and a significant reduction in SARS-CoV-2 infection and replication in-vitro.	Calcium	48-55	surface glycoprotein	Severe acute respiratory syndrome coronavirus 2	179-184