PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 3309313-3 1987 The compounds were derived from the renin substrate by replacing the scissile amide bond with a transition-state mimic and by incorporating bioisosteric replacements for the Val-10 amide bond. val-10 amide 174-186 renin Homo sapiens 36-41