PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
30875347-7	2019	PTEN knockdown impaired the methylxanthine derivative-mediated inhibition of PI3K/Akt/mTOR signalling.	methylxanthine	28-42	AKT serine/threonine kinase 1	Homo sapiens	82-85	
30875347-9	2019	These results show that the methylxanthine derivatives (caffeine and theophylline) effectively induce gastric cancer cell apoptosis and autophagy by PTEN activation and PI3K/Akt/mTOR pathway suppression and strongly support the use of methylxanthine derivatives as potential anticancer therapeutics.	methylxanthine	28-42	AKT serine/threonine kinase 1	Homo sapiens	174-177