PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 12542900-2 2002 It has been reported that theophylline was metabolized to 1,3-dimethyluric acid by CYP1A2 and CYP2E1 and 1-methylxanthine via CYP1A2, which was metabolized further to 1-methyluric acid via xanthine oxidase in rats. methylxanthine 107-121 cytochrome P450, family 1, subfamily a, polypeptide 2 Rattus norvegicus 126-132