PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
7545671-0	1995	Rapamycin, wortmannin, and the methylxanthine SQ20006 inactivate p70s6k by inducing dephosphorylation of the same subset of sites.	methylxanthine	31-45	ribosomal protein S6 kinase, polypeptide 1	Mus musculus	65-71	
7545671-7	1995	However, other agents that raise intracellular cAMP levels have no inhibitory effect, leading to the hypothesis that the inhibitory actions of methylxanthines on p70s6k activity are not through activating protein kinase A but through inhibition of an upstream kinase.	methylxanthine	143-158	ribosomal protein S6 kinase, polypeptide 1	Mus musculus	162-168	
7545671-8	1995	Together the results indicate that there are two kinase signaling pathways that must converge to activate p70s6k and that only one of these pathways is sensitive to rapamycin, wortmannin, and methylxanthine inhibition.	methylxanthine	192-206	ribosomal protein S6 kinase, polypeptide 1	Mus musculus	106-112