PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 1281035-5 1992 Although their mechanism of action is unknown, one class of compounds, the methylxanthines, have been shown to reverse a fundamental CF abnormality in CF salivary cells and in non-epithelial cells overexpressing CFTR. methylxanthine 75-90 CF transmembrane conductance regulator Homo sapiens 212-216