PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 19018984-3 2009 Recently, we demonstrated that the methylxanthine derivate caffeine leads to an upregulation of peroxisome proliferator activated receptor gamma (PPARgamma) expression in hepatocytes, thus sensitizing these cells to the well-known inhibitory effect of 15-deoxy-Delta(12,14)-prostaglandin J(2) (15-d-PGJ(2)) on CTGF expression. methylxanthine 35-49 peroxisome proliferator activated receptor gamma Homo sapiens 96-144 19018984-3 2009 Recently, we demonstrated that the methylxanthine derivate caffeine leads to an upregulation of peroxisome proliferator activated receptor gamma (PPARgamma) expression in hepatocytes, thus sensitizing these cells to the well-known inhibitory effect of 15-deoxy-Delta(12,14)-prostaglandin J(2) (15-d-PGJ(2)) on CTGF expression. methylxanthine 35-49 peroxisome proliferator activated receptor gamma Homo sapiens 146-155 19018984-8 2009 CONCLUSIONS: In conclusion, our data thus proposed an increased suitability of these patient groups for therapeutic approaches with drugs inducing PPARgamma expression, such as methylxanthine derivates. methylxanthine 177-191 peroxisome proliferator activated receptor gamma Homo sapiens 147-156