PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 22673619-0 2012 Noncompetitive blocking of human GLUT1 hexose transporter by methylxanthines reveals an exofacial regulatory binding site. methylxanthine 61-76 solute carrier family 2 member 1 Homo sapiens 33-38 22673619-4 2012 The displacement of previously bound cytochalasin B revealed a direct interaction between the methylxanthines and GLUT1. methylxanthine 94-109 solute carrier family 2 member 1 Homo sapiens 114-119 22673619-10 2012 Therefore, the methylxanthine moiety may become an attractive framework for the design of novel specific noncompetitive facilitative GLUT inhibitors. methylxanthine 15-29 solute carrier family 2 member 1 Homo sapiens 133-137 11477212-0 2001 Glucose transporter type 1 deficiency syndrome (Glut1DS): methylxanthines potentiate GLUT1 haploinsufficiency in vitro. methylxanthine 58-73 solute carrier family 2 member 1 Homo sapiens 48-55 11477212-0 2001 Glucose transporter type 1 deficiency syndrome (Glut1DS): methylxanthines potentiate GLUT1 haploinsufficiency in vitro. methylxanthine 58-73 solute carrier family 2 member 1 Homo sapiens 85-90 11477212-11 2001 Our study suggests that Glut1DS patients may have a reduced safety margin for methylxanthines. methylxanthine 78-93 solute carrier family 2 member 1 Homo sapiens 24-31 11477212-12 2001 Consumption of methylxanthine-containing products may aggravate the neurologic symptoms associated with the Glut1DS. methylxanthine 15-29 solute carrier family 2 member 1 Homo sapiens 108-115