PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 29069086-7 2017 By analyzing telomere length and dNTP levels in different mutants showing changes in RNR complex composition and activity we provide evidence that the Mec1ATR checkpoint protein promotes telomere elongation by increasing both dNTP levels and dGTP ratios through Rnr1 upregulation in a mechanism that cannot be replaced by its homolog Rnr3. deoxyguanosine triphosphate 242-246 ribonucleotide-diphosphate reductase subunit RNR3 Saccharomyces cerevisiae S288C 334-338