PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 12504787-7 2003 P2Y(2) and P2Y(4) receptors might also be involved in nucleotide responses, since UTPgammaS and adenosine 5"-O-3-thiotriphosphate (ATPgammaS) were of similar potency. adenosine 5'-O-(3-thiotriphosphate) 96-129 purinergic receptor P2Y2 Rattus norvegicus 0-6 16597733-2 2006 We demonstrate here a previously unappreciated role for extracellular nucleotide signaling through the P2Y2 receptor in the survival of neurons: PC12 (pheochromocytoma 12) cells and dorsal root ganglion neurons are protected from serum starvation-induced apoptosis by ATP, UTP, and ATPgammaS, an effect mediated via P2Y2 receptors, as demonstrated by small interfering RNA and genetic knock-out models. adenosine 5'-O-(3-thiotriphosphate) 282-291 purinergic receptor P2Y2 Rattus norvegicus 103-107 16365320-3 2005 We found that 5"-O-(3-thio)triphosphate (ATPgammaS) activation of the G protein-coupled receptor P2Y(2) in the presence of nerve growth factor leads to the colocalization and association of tyrosine receptor kinase A and P2Y(2) receptors and is required for enhanced neuronal differentiation. adenosine 5'-O-(3-thiotriphosphate) 41-50 purinergic receptor P2Y2 Rattus norvegicus 97-103 12588704-1 2003 SPOC1 cells, which are a mucin-secreting model of rat airway goblet cells, possess a luminal P2Y2 purinoceptor through which UTP, ATP, and ATPgammaS stimulate secretion with EC50 values of approximately 3 microM. adenosine 5'-O-(3-thiotriphosphate) 139-148 purinergic receptor P2Y2 Rattus norvegicus 93-97 12504787-7 2003 P2Y(2) and P2Y(4) receptors might also be involved in nucleotide responses, since UTPgammaS and adenosine 5"-O-3-thiotriphosphate (ATPgammaS) were of similar potency. adenosine 5'-O-(3-thiotriphosphate) 131-140 purinergic receptor P2Y2 Rattus norvegicus 0-6 10960068-7 2000 The selective P2Y(6) agonist, UDPbetaS, and the P2Y(2)/P2Y(4)-receptor agonists UTPgammaS and adenosine 5"-O-3-thiotriphosphate (ATPgammaS) were considerably more potent and efficacious (E:(max) approximately 250% of 60 mM K(+)). adenosine 5'-O-(3-thiotriphosphate) 94-127 purinergic receptor P2Y2 Rattus norvegicus 48-54 9689011-5 1998 Also, coincubation with either 10(-4) M of UTP, ATP, or ATPgammaS inhibited LPS/IFN-gamma-induced nitrite production by 29.9 +/- 5.8, 36.4 +/- 4.3, and 50.3 +/- 6.5%, respectively, indicating involvement of purinergic P2Y2 receptors. adenosine 5'-O-(3-thiotriphosphate) 56-65 purinergic receptor P2Y2 Rattus norvegicus 218-222