PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
34590769-5	2021	Subsequently, a ketoreductase ChaE rearranges the carbon skeleton and afford the alpha-pyrone containing pentacyclic intermediate in an NADPH-dependent manner, presumably via a cascade reactions including the reduction of the lactone carbonyl group, Aldol-type reaction, followed by a spontaneous gamma-lactone ring formation, and aromatization.	4-hexanolide	297-310	2,4-dienoyl-CoA reductase 1	Homo sapiens	136-141