PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
33607168-2	2021	Kynurenine 3-monooxygenase (KMO) is a pivotal enzyme in the metabolism of KYN to 3-hydroxykynurenine.	3-hydroxykynurenine	81-100	kynurenine 3-monooxygenase (kynurenine 3-hydroxylase)	Mus musculus	0-26	
35204197-1	2022	Kynurenine 3-monooxygenase (KMO), a key player in the kynurenine pathway (KP) of tryptophan degradation, regulates the synthesis of the neuroactive metabolites 3-hydroxykynurenine (3-HK) and kynurenic acid (KYNA).	3-hydroxykynurenine	160-179	kynurenine 3-monooxygenase (kynurenine 3-hydroxylase)	Mus musculus	0-26	
35204197-1	2022	Kynurenine 3-monooxygenase (KMO), a key player in the kynurenine pathway (KP) of tryptophan degradation, regulates the synthesis of the neuroactive metabolites 3-hydroxykynurenine (3-HK) and kynurenic acid (KYNA).	3-hydroxykynurenine	160-179	kynurenine 3-monooxygenase (kynurenine 3-hydroxylase)	Mus musculus	28-31	
33607168-2	2021	Kynurenine 3-monooxygenase (KMO) is a pivotal enzyme in the metabolism of KYN to 3-hydroxykynurenine.	3-hydroxykynurenine	81-100	kynurenine 3-monooxygenase (kynurenine 3-hydroxylase)	Mus musculus	28-31	
30760699-3	2019	We show that KMO is highly expressed in the kidney and exerts major metabolic control over the biologically active kynurenine metabolites 3-hydroxykynurenine, kynurenic acid, and downstream metabolites.	3-hydroxykynurenine	138-157	kynurenine 3-monooxygenase (kynurenine 3-hydroxylase)	Mus musculus	13-16	
32151061-4	2020	We generated a knockout mouse strain of kynurenine 3-monooxygenase (KMO), an enzyme in the kynurenine pathway that produces neurotoxic 3-hydroxykynurenine.	3-hydroxykynurenine	135-154	kynurenine 3-monooxygenase (kynurenine 3-hydroxylase)	Mus musculus	40-66	
32151061-4	2020	We generated a knockout mouse strain of kynurenine 3-monooxygenase (KMO), an enzyme in the kynurenine pathway that produces neurotoxic 3-hydroxykynurenine.	3-hydroxykynurenine	135-154	kynurenine 3-monooxygenase (kynurenine 3-hydroxylase)	Mus musculus	68-71	
27889626-4	2017	Kynurenine 3-monooxygenase (KMO) is one of the key regulatory enzymes, which metabolizes kynurenine to 3-hydroxykynurenine in the KP.	3-hydroxykynurenine	103-122	kynurenine 3-monooxygenase (kynurenine 3-hydroxylase)	Mus musculus	0-26	
30354938-7	2018	Conversely, 3-hydroxykynurenine and quinolinic acid levels in the fetal brain tended to be lower in heterozygous animals derived from kynurenine-treated Kmo+/- mice than in corresponding Kmo+/+ offspring.	3-hydroxykynurenine	12-31	kynurenine 3-monooxygenase (kynurenine 3-hydroxylase)	Mus musculus	153-156	
29879409-1	2018	Kynurenine 3-monooxygenase (KMO) is an essential enzyme of the kynurenine pathway, converting kynurenine into 3-hydroxykynurenine.	3-hydroxykynurenine	110-129	kynurenine 3-monooxygenase (kynurenine 3-hydroxylase)	Mus musculus	0-26	
29879409-1	2018	Kynurenine 3-monooxygenase (KMO) is an essential enzyme of the kynurenine pathway, converting kynurenine into 3-hydroxykynurenine.	3-hydroxykynurenine	110-129	kynurenine 3-monooxygenase (kynurenine 3-hydroxylase)	Mus musculus	28-31	
28187857-1	2017	BACKGROUND: Kynurenine 3-monooxygenase converts kynurenine to 3-hydroxykynurenine, and its inhibition shunts the kynurenine pathway-which is implicated as dysfunctional in various psychiatric disorders-toward enhanced synthesis of kynurenic acid, an antagonist of both alpha7 nicotinic acetylcholine and N-methyl-D-aspartate receptors.	3-hydroxykynurenine	62-81	kynurenine 3-monooxygenase (kynurenine 3-hydroxylase)	Mus musculus	12-38	
27889626-4	2017	Kynurenine 3-monooxygenase (KMO) is one of the key regulatory enzymes, which metabolizes kynurenine to 3-hydroxykynurenine in the KP.	3-hydroxykynurenine	103-122	kynurenine 3-monooxygenase (kynurenine 3-hydroxylase)	Mus musculus	28-31	
23575632-2	2013	KMO is a flavin adenine dinucleotide (FAD)-dependent monooxygenase and is located in the outer mitochondrial membrane where it converts l-kynurenine to 3-hydroxykynurenine.	3-hydroxykynurenine	152-171	kynurenine 3-monooxygenase (kynurenine 3-hydroxylase)	Mus musculus	0-3	
27754481-8	2016	Direct administration of 3-hydroxykynurenine, the metabolic product of KMO, caused a dose-dependent increase in depressive-like behaviors.	3-hydroxykynurenine	25-44	kynurenine 3-monooxygenase (kynurenine 3-hydroxylase)	Mus musculus	71-74	
24189070-4	2013	As expected, Kmo(-/-) mice showed substantial reductions in the levels of its enzymatic product, 3-hydroxykynurenine, in liver, brain, and plasma.	3-hydroxykynurenine	97-116	kynurenine 3-monooxygenase (kynurenine 3-hydroxylase)	Mus musculus	13-16