PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
18025273-8	2007	In a cell death ELISA, 17-DMAG markedly induced apoptosis in both p53-wt and p53-deficient cells.	17-(dimethylaminoethylamino)-17-demethoxygeldanamycin	23-30	tumor protein p53	Homo sapiens	66-69	
21663398-0	2011	Geldanamycin analog 17-DMAG limits apoptosis in human peripheral blood cells by inhibition of p53 activation and its interaction with heat-shock protein 90 kDa after exposure to ionizing radiation.	17-(dimethylaminoethylamino)-17-demethoxygeldanamycin	20-27	tumor protein p53	Homo sapiens	94-97	
21663398-2	2011	We tested the effect of 17-dimethylamino-ethylamino-17-demethoxygeldanamycin (17-DMAG) on p53 expression and function after radiation exposure.	17-(dimethylaminoethylamino)-17-demethoxygeldanamycin	24-76	tumor protein p53	Homo sapiens	90-93	
21663398-2	2011	We tested the effect of 17-dimethylamino-ethylamino-17-demethoxygeldanamycin (17-DMAG) on p53 expression and function after radiation exposure.	17-(dimethylaminoethylamino)-17-demethoxygeldanamycin	78-85	tumor protein p53	Homo sapiens	90-93	
21663398-7	2011	Analysis of p53-Hsp90 interaction in ex vivo cell lysates indicated that the binding between the two molecules occurred after irradiation but 17-DMAG prevented the binding.	17-(dimethylaminoethylamino)-17-demethoxygeldanamycin	142-149	tumor protein p53	Homo sapiens	12-15	
18025273-8	2007	In a cell death ELISA, 17-DMAG markedly induced apoptosis in both p53-wt and p53-deficient cells.	17-(dimethylaminoethylamino)-17-demethoxygeldanamycin	23-30	tumor protein p53	Homo sapiens	77-80	
18025273-11	2007	Importantly, combining oxaliplatin with 17-DMAG in vivo significantly improved growth inhibitory and proapoptotic effects on p53-deficient cells, compared with either substance alone.	17-(dimethylaminoethylamino)-17-demethoxygeldanamycin	40-47	tumor protein p53	Homo sapiens	125-128	
17085670-0	2006	Schedule-dependent synergy between the heat shock protein 90 inhibitor 17-(dimethylaminoethylamino)-17-demethoxygeldanamycin and doxorubicin restores apoptosis to p53-mutant lymphoma cell lines.	17-(dimethylaminoethylamino)-17-demethoxygeldanamycin	71-124	tumor protein p53	Homo sapiens	163-166	
17085670-13	2006	Administration of DMAG before doxorubicin resulted in G1-S arrest and protection from apoptosis, leading to additive or antagonistic interactions that were exacerbated by p53 mutation.	17-(dimethylaminoethylamino)-17-demethoxygeldanamycin	18-22	tumor protein p53	Homo sapiens	171-174	
17085670-14	2006	CONCLUSIONS: Administration of DMAG to doxorubicin-primed cells induced premature mitosis and had a synergistic effect on apoptosis regardless of p53 status.	17-(dimethylaminoethylamino)-17-demethoxygeldanamycin	31-35	tumor protein p53	Homo sapiens	146-149