PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
2118156-10	1990	Based on these observations, we suggest that IFN-gamma antagonizes the colony inducing effect of IL-4 and IgE-Ag stimulation which act synergistically with IL-3 on CTMC.	ctmc	164-168	interleukin 3	Mus musculus	156-160	
1375244-9	1992	However, most mast cells which were induced by rrSCF+IL-3 from peritoneal CTMC contained berberine(-)-safranin(-)-Alcian blue(+) granules.	ctmc	74-78	interleukin 3	Mus musculus	53-57	
1375244-10	1992	Although IL-4 exhibited little synergism with rrSCF in the induction of CTMC proliferation, the addition of IL-4 to the culture containing rrSCF+IL-3 resulted in an increase in mast cells which retained CTMC characteristics.	ctmc	203-207	interleukin 3	Mus musculus	145-149	
1381628-7	1992	Also, rrSCF164 induced +/+-CMC to acquire the phenotypes of CTMC in the medium containing IL-3.	ctmc	60-64	interleukin 3	Mus musculus	90-94	
2118156-3	1990	In addition, mAb to mouse IFN-gamma neutralized the suppressive effect of IFN-gamma on CTMC proliferation supported by the combination of IL-3 + IL-4.	ctmc	87-91	interleukin 3	Mus musculus	138-142	
2118156-6	1990	IFN-gamma had suppressive effects on CTMC after preincubation with IL-3 + IL-4.	ctmc	37-41	interleukin 3	Mus musculus	67-71	
2118156-7	1990	These preincubation studies suggest that IFN-gamma exerts a reversible inhibitory effect on CTMC which have entered into a proliferative state by IL-3 + IL-4, and has neither cytotoxic nor irreversible suppressive effects on resting CTMC in cultures containing IL-3 alone.	ctmc	92-96	interleukin 3	Mus musculus	146-150	
2118156-8	1990	CTMC proliferation after stimulation with the cross-linking of cell-bound IgE by specific Ag in the presence of IL-3 was also suppressed by IFN-gamma.	ctmc	0-4	interleukin 3	Mus musculus	112-116	
2118156-9	1990	By contrast, proliferation of CTMC induced by the combination of 12-O-tetradecanoyl phorbol-13-acetate + IL-3 was not affected by the addition of IFN-gamma to the culture.	ctmc	30-34	interleukin 3	Mus musculus	105-109	
3261278-3	1988	The number of mast cells in the spleen, approximately 60% of which were formalin-resistant and were assumed as connective tissue type mast cells (CTMC), increased 3-fold by IL-3 treatment.	ctmc	146-150	interleukin 3	Mus musculus	173-177	
2473160-1	1989	Crosslinking of cell-bound IgE on mouse connective tissue-type mast cells (CTMC) by multivalent antigen or anti-IgE antibody induced clonal growth of CTMC in methylcellulose culture containing IL-3.	ctmc	75-79	interleukin 3	Mus musculus	193-197	
2473160-1	1989	Crosslinking of cell-bound IgE on mouse connective tissue-type mast cells (CTMC) by multivalent antigen or anti-IgE antibody induced clonal growth of CTMC in methylcellulose culture containing IL-3.	ctmc	150-154	interleukin 3	Mus musculus	193-197	
2473160-2	1989	Continuous presence of antigen, IgE antibody, and IL-3 in culture was required for extensive proliferation of CTMC.	ctmc	110-114	interleukin 3	Mus musculus	50-54	
2473160-7	1989	These results suggest that stimulation of CTMC via IgE receptors not only triggers the release of chemical mediators from the cells but induces clonal growth of CTMC in the presence of IL-3.	ctmc	42-46	interleukin 3	Mus musculus	185-189	
2473160-7	1989	These results suggest that stimulation of CTMC via IgE receptors not only triggers the release of chemical mediators from the cells but induces clonal growth of CTMC in the presence of IL-3.	ctmc	161-165	interleukin 3	Mus musculus	185-189	
2295001-3	1990	Pretreatment of CTMC with IL-3 and/or IL-4 indicated that the sustained presence of both factors was required for the development of type 1 mast cell colonies.	ctmc	16-20	interleukin 3	Mus musculus	26-30	
2295001-7	1990	The purified CTMC cultured with IL-3 retained the morphological and cytochemical characteristics of CTMC, as well as proliferative ability.	ctmc	13-17	interleukin 3	Mus musculus	32-36	
2295001-7	1990	The purified CTMC cultured with IL-3 retained the morphological and cytochemical characteristics of CTMC, as well as proliferative ability.	ctmc	100-104	interleukin 3	Mus musculus	32-36	
2295001-8	1990	These observations indicate that IL-3 supports the survival of CTMC in methylcellulose culture and that IL-4 triggers and supports CTMC proliferation synergistically with IL-3.	ctmc	63-67	interleukin 3	Mus musculus	33-37	
2295001-9	1990	The serum-free culture of purified CTMC and the culture of single CTMC demonstrated that the synergistic effect of IL-3 and IL-4 on colony growth and the surviving effect of IL-3 on CTMC require no influence from accessory cells or other humoral factors.	ctmc	66-70	interleukin 3	Mus musculus	115-119	
2295001-9	1990	The serum-free culture of purified CTMC and the culture of single CTMC demonstrated that the synergistic effect of IL-3 and IL-4 on colony growth and the surviving effect of IL-3 on CTMC require no influence from accessory cells or other humoral factors.	ctmc	66-70	interleukin 3	Mus musculus	115-119	
3549363-7	1987	Thus, interleukin 3-dependent mouse BMMC can be induced to undergo phenotypic changes in staining characteristics, histamine content, glycosaminoglycan structure, and metabolism of arachidonic acid to resemble heparin-containing CTMC.	ctmc	229-233	interleukin 3	Mus musculus	6-19