PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 12816347-5 2003 Drug molecules such as oral active beta-lactam antibiotics, bestatin, prodrugs of aciclovir and ganciclovir have oral bioavailabilities, which largely are a result of their interaction with PepT1. Ganciclovir 96-107 solute carrier family 15 member 1 Homo sapiens 190-195 15482169-3 2004 Valganciclovir is a highly recognized substrate of the intestinal peptide transporter PEPT1, which underlies the tenfold higher bioavailability of ganciclovir after valganciclovir compared to oral ganciclovir administration. Ganciclovir 3-14 solute carrier family 15 member 1 Homo sapiens 86-91 15482169-3 2004 Valganciclovir is a highly recognized substrate of the intestinal peptide transporter PEPT1, which underlies the tenfold higher bioavailability of ganciclovir after valganciclovir compared to oral ganciclovir administration. Ganciclovir 147-158 solute carrier family 15 member 1 Homo sapiens 86-91 10824137-0 2000 Transport of valganciclovir, a ganciclovir prodrug, via peptide transporters PEPT1 and PEPT2. Ganciclovir 16-27 solute carrier family 15 member 1 Homo sapiens 77-82 10824137-2 2000 We investigated the role of the intestinal peptide transporter PEPT1 in this process by comparing the interaction of ganciclovir and valganciclovir with the transporter in different experimental systems. Ganciclovir 117-128 solute carrier family 15 member 1 Homo sapiens 63-68 10824137-9 2000 Valganciclovir, but not ganciclovir, induced inward currents in PEPT1-expressing oocytes. Ganciclovir 3-14 solute carrier family 15 member 1 Homo sapiens 64-69 24943988-2 2015 Reports from our laboratory have suggested that dipeptide ester prodrugs of GCV exhibit high affinity towards the oligopeptide transporter hPEPT1 and therefore seem to be promising candidates for the treatment of oral herpes virus infections. Ganciclovir 76-79 solute carrier family 15 member 1 Homo sapiens 139-145