PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 15322248-4 2004 The YC-1-induced increase in COX activity was also blocked by manumycin A, wortmannin, PDTC, and the dominant-negative mutants for Ras (RasN17), Akt (Akt DN), and IkappaBalpha (IkappaBalphaM). manumycin 62-73 RNA binding motif single stranded interacting protein 1 Homo sapiens 4-8 15322248-9 2004 Likewise, YC-1-induced IKKalpha/beta activation was inhibited by ODQ, KT-5823, manumycin A, wortmannin, and an Akt inhibitor. manumycin 79-90 RNA binding motif single stranded interacting protein 1 Homo sapiens 10-14 15322248-10 2004 Furthermore, YC-1-induced COX-2 promoter activity was inhibited by manumycin A, RasN17, Akt DN, PDTC, and IkappaBalphaM. manumycin 67-78 RNA binding motif single stranded interacting protein 1 Homo sapiens 13-17 15322248-8 2004 YC-1-induced kappaB-luciferase activity was inhibited by ODQ, KT-5823, manumycin A, wortmannin, an Akt inhibitor, PDTC, RasN17, Akt DN, and IkappaBalphaM. manumycin 71-82 RNA binding motif single stranded interacting protein 1 Homo sapiens 0-4 19717011-5 2009 YC-1-mediated Raf-1 activation was inhibited by an sGC inhibitor (ODQ), a PKG inhibitor (KT-5823), a Ras inhibitor (manumycin A), a dominant negative Ras mutant (RasN17), a protein kinase C-alpha (PKC-alpha) inhibitor (Ro 32-0432), and a phosphoinositide-3-OH-kinase (PI3K) inhibitor (LY 294002). manumycin 116-127 RNA binding motif single stranded interacting protein 1 Homo sapiens 0-4 19717011-6 2009 Pretreatment of A549 cells with either manumycin A or GW 5074 attenuated YC-1-induced p44/42 MAPK activation. manumycin 39-50 RNA binding motif single stranded interacting protein 1 Homo sapiens 73-77