PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 18523246-3 2008 In this study, we determined whether the lysophospholipids, i.e., LPC and sphingosylphosphorylcholine (SPC), modulate the ATP-induced release and processing of IL-1beta mediated by P2X7R in mouse MG6 microglial cells. Lysophosphatidylcholines 66-69 interleukin 1 beta Mus musculus 160-168 25004092-4 2014 We find that the proinflammatory cytokine combination IL-1beta+IFNgamma, induces: a) ER stress, mSREBP-1, and iPLA2beta, b) lysophosphatidylcholine (LPC) generation, c) neutral sphingomyelinase-2 (NSMase2), d) ceramide accumulation, e) mitochondrial membrane decompensation, f) caspase-3 activation, and g) beta-cell apoptosis. Lysophosphatidylcholines 124-147 interleukin 1 beta Mus musculus 54-62