PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 20118535-3 2010 Hypothemycin normalized the morphology and inhibited anchorage-independent growth of Ki-ras transformed normal rat kidney (NRK) cells with selectivity and potency comparable to or greater than that of the MEK inhibitor U0126. hypothemycin 0-12 KRAS proto-oncogene, GTPase Rattus norvegicus 85-91 20118535-4 2010 In Ki-ras-transformed and phorbol 12-myristate 13-acetate (PMA)-treated NRK cells, hypothemycin blocked ERK activation but showed a minimal effect on autophosphorylation of protein kinase D1 (PKD1), another kinase containing the conserved cysteine. hypothemycin 83-95 KRAS proto-oncogene, GTPase Rattus norvegicus 3-9