PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 24623817-7 2014 Loss of RECQL1 results in dysfunctional telomeres, telomere loss and telomere shortening, elevation of telomere sister-chromatid exchanges and increased aphidicolin-induced telomere fragility, indicating a role for RECQL1 in telomere maintenance. Aphidicolin 153-164 RecQ like helicase Homo sapiens 8-14 23601052-6 2013 We have also tested the sensitivity of RECQ1-depleted cells to aphidicolin induced replication stress. Aphidicolin 63-74 RecQ like helicase Homo sapiens 39-44 23601052-9 2013 Consistent with a role in promoting fork recovery or repair, RECQ1 is specifically enriched at two major fragile sites FRA3B and FRA16D where replication forks have stalled following aphidicolin treatment. Aphidicolin 183-194 RecQ like helicase Homo sapiens 61-66 23601052-10 2013 RECQ1-depletion results in attenuated checkpoint activation in response to replication stress, increased sensitivity to aphidicolin and chromosomal instability. Aphidicolin 120-131 RecQ like helicase Homo sapiens 0-5