PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
16581540-3	2006	We have previously shown that aquaglyceroporin channels, including Escherichia coli GlpF, Saccharomyces cerevisiae Fps1p, AQP7, and AQP9 from rat and human, conduct trivalent inorganic arsenic [As(III)] as arsenic trioxide, the protonated form of arsenite.	arsenite	247-255	aquaporin 9	Homo sapiens	132-136	
28798983-9	2017	AQP9 transport of MSeA, selenite and lactate is all inhibited by a previously identified AQP9 inhibitor, phloretin, and the AQP9 substrate arsenite (AsIII).	arsenite	139-147	aquaporin 9	Homo sapiens	0-4	
23563754-8	2013	These findings suggest that the AQP9 expression status of APL patients is a predictive marker for the successful outcome of ATO treatment, since AQP9 plays a pivotal role in various arsenite-mediated biological effects on normal and cancer cells.	arsenite	182-190	aquaporin 9	Homo sapiens	32-36	
23563754-8	2013	These findings suggest that the AQP9 expression status of APL patients is a predictive marker for the successful outcome of ATO treatment, since AQP9 plays a pivotal role in various arsenite-mediated biological effects on normal and cancer cells.	arsenite	182-190	aquaporin 9	Homo sapiens	145-149	
19802720-1	2010	Liver aquaglyceroporin AQP9 facilitates movement of trivalent inorganic arsenite (As(III)) and organic monomethylarsonous acid (MAs(III)).	arsenite	72-80	aquaporin 9	Homo sapiens	23-27	
25258480-0	2014	Comparative Molecular Docking Studies with ABCC1 and Aquaporin 9 in the Arsenite Complex Efflux.	arsenite	72-80	aquaporin 9	Homo sapiens	53-64	
22130551-3	2012	To understand the role of aberrant expression of AQP in this disease, we over-expressed AQP3 and AQP9 in human melanoma WM266.4 cells and found that both AQPs significantly increased the chemoresistance of WM266.4 cells to arsenite.	arsenite	223-231	aquaporin 9	Homo sapiens	97-101	
22130551-4	2012	Functional studies showed that AQP3 and AQP9 can inhibit cell apoptosis induced by arsenite through down-regulating p53 and up-regulating Bcl-2 and XIAP.	arsenite	83-91	aquaporin 9	Homo sapiens	40-44	
22130551-5	2012	Our data suggest the implication of APQ in melanoma progression and that the over-expression of AQP3 and AQP9 contributes to the chemoresistance of melanoma to arsenite.	arsenite	160-168	aquaporin 9	Homo sapiens	105-109	
19341753-5	2009	Furthermore, overexpression of AQP9 in HEK293 cells led to the enhancement of intracellular arsenic concentration, resulting in enhanced cytotoxicity after arsenite exposure.	arsenite	156-164	aquaporin 9	Homo sapiens	31-35	
11972053-0	2002	Arsenite transport by mammalian aquaglyceroporins AQP7 and AQP9.	arsenite	0-8	aquaporin 9	Homo sapiens	59-63	
11972053-11	2002	These results suggest that AQP9 and AQP7 may be a major routes of arsenite uptake into mammalian cells, an observation potentially of large importance for understanding the action of arsenite as a human toxin and carcinogen, as well as its efficacy as a chemotherapeutic agent for acute promyelocytic leukemia.	arsenite	66-74	aquaporin 9	Homo sapiens	27-31	
11972053-11	2002	These results suggest that AQP9 and AQP7 may be a major routes of arsenite uptake into mammalian cells, an observation potentially of large importance for understanding the action of arsenite as a human toxin and carcinogen, as well as its efficacy as a chemotherapeutic agent for acute promyelocytic leukemia.	arsenite	183-191	aquaporin 9	Homo sapiens	27-31