PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 21292642-8 2011 Stably expressing ZEB1 alone in parental nontransformed p53(low)HBECs was sufficient to deplete miR-200, induce EMT and cause cell transformation, phenocopying the oncogenic effect of 16-week arsenite exposure. arsenite 192-200 zinc finger E-box binding homeobox 1 Homo sapiens 18-22 29216394-0 2018 CircLRP6 Regulation of ZEB1 via miR-455 Is Involved in the Epithelial-Mesenchymal Transition During Arsenite-Induced Malignant Transformation of Human Keratinocytes. arsenite 100-108 zinc finger E-box binding homeobox 1 Homo sapiens 23-27 29216394-5 2018 For these cells, chronic exposure to arsenite caused an increase of circLRP6 and the transcription factor ZEB1, which induced the EMT. arsenite 37-45 zinc finger E-box binding homeobox 1 Homo sapiens 106-110 29216394-8 2018 These results suggest that, in HaCaT cells, arsenite increases circLRP6 levels, which act as a sponge for miR-455 and up-regulate the miR-455 target, ZEB1, which subsequently induces the EMT, thus promoting malignant transformation. arsenite 44-52 zinc finger E-box binding homeobox 1 Homo sapiens 150-154 29216394-9 2018 Thus, for HaCaT cells chronically exposed to arsenite, circLRP6 via miR-455 regulation of ZEB1 is involved in the EMT during malignant transformation. arsenite 45-53 zinc finger E-box binding homeobox 1 Homo sapiens 90-94 30167605-0 2018 Circ008913, via miR-889 regulation of DAB2IP/ZEB1, is involved in the arsenite-induced acquisition of CSC-like properties by human keratinocytes in carcinogenesis. arsenite 70-78 zinc finger E-box binding homeobox 1 Homo sapiens 45-49 30167605-6 2018 In HaCaT cells, arsenite induced increases of mRNA levels of the genes for cell-surface markers (k5 and CD34) of skin stem cells, decreases of DAB2IP, and increases of ZEB1. arsenite 16-24 zinc finger E-box binding homeobox 1 Homo sapiens 168-172 30167605-9 2018 These results suggest that, in HaCaT cells, arsenite decreases circ008913 levels, which act as a sponge for miR-889 and down-regulate the miR-889 target, DAB2IP, which, in turn, up-regulates ZEB1, increases mRNA levels of the cell-surface markers of skin stem cells, and is involved in arsenite-induced acquisition of CSC-like properties that lead to malignant transformation. arsenite 44-52 zinc finger E-box binding homeobox 1 Homo sapiens 191-195