PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
12675602-9	2003	The most stable CPA-glyoxyl derivative could be efficiently used in the hydrolysis of long-chain peptides at high temperature (e.g., 60 degrees C), being able to release 2-fold more aromatic amino acids (Tyr, Phe, and Trp) than the soluble enzyme, under the same operational conditions.	Phenylalanine	209-212	carboxypeptidase A1	Homo sapiens	16-19	
3718539-2	1986	However, both CPB and CPA degraded the des-Arg derivatives to remove the C-terminal phenylalanine.	Phenylalanine	84-97	carboxypeptidase A1	Homo sapiens	22-25	
3718539-3	1986	The inhibitory effect of phosphate ions upon this activity of CPB (but not CPA) suggests that CPA may be responsible for the formation of free phenylalanine seen upon degradation of kinins in plasma or serum.	Phenylalanine	143-156	carboxypeptidase A1	Homo sapiens	94-97	
7082637-4	1982	The CPA-catalyzed hydrolysis of Z-Glys-Phe was shown to involve only C-N bond cleavage, to give carbobenzoxythioglycine and phenylalanine.	Phenylalanine	124-137	carboxypeptidase A1	Homo sapiens	4-7	
27841396-8	2016	However, for the substrate mutant that contains Asp instead of Phe at the C-terminus, one CPA mutant exhibits a reasonable activity, as predicted across the theoretical methods.	Phenylalanine	63-66	carboxypeptidase A1	Homo sapiens	90-93	
9840967-3	1998	BSA contains several electrostatic, hydrogen bonding and hydrophobic binding sites for potential interaction with the metal complexes, and CPA contains a specific phenylalanine binding site.	Phenylalanine	163-176	carboxypeptidase A1	Homo sapiens	139-142	
7834611-4	1995	When the lung tumor cells were treated with CPA conjugated to KS1/4 (a mAb targeted to these cells) and excess conjugate removed by extensive washing, the ID50 for MTX-Phe improved from 2.2 x 10(-6) M (no enzyme present) to 6.3 x 10(-8) M; the latter value was comparable to that of the parent drug MTX (4.5 x 10(-8) M).	Phenylalanine	168-171	carboxypeptidase A1	Homo sapiens	44-47