PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 10493942-4 1999 BP1-E cells, derived from the immortalized MCF-10F cells transformed by the carcinogen benzo(a)pyrene (BP), express in vitro growth advantage, anchorage independence, enhanced chemoinvasiveness, loss of ductulogenic capabilities and tumorigenesis in a heterologous host. Benzo(a)pyrene 87-101 BP1 Homo sapiens 0-3 21552801-2 1995 The treatment of MCF 10F with BP gave rise to different clones designated BP1 and BP1E, the latter being a tumorigenic cell line. Benzo(a)pyrene 30-32 BP1 Homo sapiens 74-77 10746437-1 1999 When transfected to benzo[a]pyrene (BP)-transformed MCF-10F human breast epithelial cells (BP1 cell line) the c-Ha-ras oncogene has proven to enhance the neoplastic changes initiated by exposure to BP, giving rise to an aggressive tumorigenic cell line, BP1-Tras. Benzo(a)pyrene 20-34 BP1 Homo sapiens 91-94 10746437-1 1999 When transfected to benzo[a]pyrene (BP)-transformed MCF-10F human breast epithelial cells (BP1 cell line) the c-Ha-ras oncogene has proven to enhance the neoplastic changes initiated by exposure to BP, giving rise to an aggressive tumorigenic cell line, BP1-Tras. Benzo(a)pyrene 20-34 BP1 Homo sapiens 254-257 10746437-1 1999 When transfected to benzo[a]pyrene (BP)-transformed MCF-10F human breast epithelial cells (BP1 cell line) the c-Ha-ras oncogene has proven to enhance the neoplastic changes initiated by exposure to BP, giving rise to an aggressive tumorigenic cell line, BP1-Tras. Benzo(a)pyrene 36-38 BP1 Homo sapiens 91-94 10746437-1 1999 When transfected to benzo[a]pyrene (BP)-transformed MCF-10F human breast epithelial cells (BP1 cell line) the c-Ha-ras oncogene has proven to enhance the neoplastic changes initiated by exposure to BP, giving rise to an aggressive tumorigenic cell line, BP1-Tras. Benzo(a)pyrene 36-38 BP1 Homo sapiens 254-257 9683293-3 1998 In vitro treatment of MCF-10F cells with benzo(a)pyrene resulted in a transformed subclone MCF-10F-BP1 (BP1). Benzo(a)pyrene 41-55 BP1 Homo sapiens 91-102 9683293-3 1998 In vitro treatment of MCF-10F cells with benzo(a)pyrene resulted in a transformed subclone MCF-10F-BP1 (BP1). Benzo(a)pyrene 41-55 BP1 Homo sapiens 99-102 10217447-8 1999 [4] The early BP component (BP1) was always localized in the fronto-central midline (overlying the mesial wall motor areas SMA and CMA). Benzo(a)pyrene 14-16 BP1 Homo sapiens 28-31 21552963-4 1995 DMBA and BP-treated cells gave rise to clones D3, D3-1, BP1 and BP1-E, respectively, all of which expressed colony formation in agar-methocel and high chemoinvasion index. Benzo(a)pyrene 9-11 BP1 Homo sapiens 56-59 21552963-4 1995 DMBA and BP-treated cells gave rise to clones D3, D3-1, BP1 and BP1-E, respectively, all of which expressed colony formation in agar-methocel and high chemoinvasion index. Benzo(a)pyrene 9-11 BP1 Homo sapiens 64-67 15547727-12 2004 Interesting, among the tumorigenic MCF-10F cells previously exposed to both BP and c-Ha-ras (BP1-Tras-3 Gy cell line), radiation increased the c-myc, c-jun, c-fos protein expression by more than 120% relative to the non-irradiated controls. Benzo(a)pyrene 76-78 BP1 Homo sapiens 93-96 21556625-3 1995 DMBA-treated cells gave rise to clones D3 and D3-1, BP-treated cells gave rise to clones BP1 and BP1-E. BP1-E cell line, derived from BP1 cell line, was tumorigenic in SCID mice. Benzo(a)pyrene 52-54 BP1 Homo sapiens 89-92 21556625-3 1995 DMBA-treated cells gave rise to clones D3 and D3-1, BP-treated cells gave rise to clones BP1 and BP1-E. BP1-E cell line, derived from BP1 cell line, was tumorigenic in SCID mice. Benzo(a)pyrene 52-54 BP1 Homo sapiens 97-100 21556625-3 1995 DMBA-treated cells gave rise to clones D3 and D3-1, BP-treated cells gave rise to clones BP1 and BP1-E. BP1-E cell line, derived from BP1 cell line, was tumorigenic in SCID mice. Benzo(a)pyrene 52-54 BP1 Homo sapiens 97-100 21556625-3 1995 DMBA-treated cells gave rise to clones D3 and D3-1, BP-treated cells gave rise to clones BP1 and BP1-E. BP1-E cell line, derived from BP1 cell line, was tumorigenic in SCID mice. Benzo(a)pyrene 52-54 BP1 Homo sapiens 97-100 15057875-1 2004 Transformation of the human breast epithelial cells (HBEC) MCF-10F with the carcinogen benz(a)pyrene (BP) into BP1-E cells resulted in the loss of the chromosome 17 p13.2 locus (D17S796 marker) and formation of colonies in agar-methocel (colony efficiency (CE)), loss of ductulogenic capacity in collagen matrix, and resistance to anti-Fas monoclonal antibody (Mab)-induced apoptosis. Benzo(a)pyrene 102-104 BP1 Homo sapiens 111-114 12655650-1 2003 BACKGROUND: A relation between the changes in DNA content and chromatin supra-organization and the expression of gradual steps of tumorigenesis has been assessed by image analysis in human breast epithelial cells (MCF-10F) treated with benzo[a]pyrene (BP) (cell lines BP1, BP1-E, BP1-Tras, and others). Benzo(a)pyrene 236-250 BP1 Homo sapiens 268-271 12655650-1 2003 BACKGROUND: A relation between the changes in DNA content and chromatin supra-organization and the expression of gradual steps of tumorigenesis has been assessed by image analysis in human breast epithelial cells (MCF-10F) treated with benzo[a]pyrene (BP) (cell lines BP1, BP1-E, BP1-Tras, and others). Benzo(a)pyrene 236-250 BP1 Homo sapiens 273-276 12655650-1 2003 BACKGROUND: A relation between the changes in DNA content and chromatin supra-organization and the expression of gradual steps of tumorigenesis has been assessed by image analysis in human breast epithelial cells (MCF-10F) treated with benzo[a]pyrene (BP) (cell lines BP1, BP1-E, BP1-Tras, and others). Benzo(a)pyrene 236-250 BP1 Homo sapiens 273-276 12655650-1 2003 BACKGROUND: A relation between the changes in DNA content and chromatin supra-organization and the expression of gradual steps of tumorigenesis has been assessed by image analysis in human breast epithelial cells (MCF-10F) treated with benzo[a]pyrene (BP) (cell lines BP1, BP1-E, BP1-Tras, and others). Benzo(a)pyrene 252-254 BP1 Homo sapiens 268-271 12655650-1 2003 BACKGROUND: A relation between the changes in DNA content and chromatin supra-organization and the expression of gradual steps of tumorigenesis has been assessed by image analysis in human breast epithelial cells (MCF-10F) treated with benzo[a]pyrene (BP) (cell lines BP1, BP1-E, BP1-Tras, and others). Benzo(a)pyrene 252-254 BP1 Homo sapiens 273-276 12655650-1 2003 BACKGROUND: A relation between the changes in DNA content and chromatin supra-organization and the expression of gradual steps of tumorigenesis has been assessed by image analysis in human breast epithelial cells (MCF-10F) treated with benzo[a]pyrene (BP) (cell lines BP1, BP1-E, BP1-Tras, and others). Benzo(a)pyrene 252-254 BP1 Homo sapiens 273-276