PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 10764626-1 2000 The P-glycoprotein (P-gp)-negative epidermoid pharyngeal carcinoma cells KB-3-1 were grown in 0.25 mM benzo[a]pyrene (BaP) for 3 months and increased resistance to doxorubicin, but not to vinblastine, colchicine, or cisplatin, was found. Benzo(a)pyrene 102-116 ATP binding cassette subfamily B member 1 Homo sapiens 4-18 10764626-3 2000 Intracellular accumulation of BaP or calcein, a substrate for P-gp and multidrug resistance protein (MRP), was not altered by inhibitors of the P-gp and MRP. Benzo(a)pyrene 30-33 ATP binding cassette subfamily B member 1 Homo sapiens 62-66 10764626-6 2000 BaP-treated KB-3-1 cells remained P-gp negative while the level of MRP was not altered. Benzo(a)pyrene 0-3 ATP binding cassette subfamily B member 1 Homo sapiens 34-38 7903198-2 1993 We previously showed that MDR cells derived from exposure to Adriamycin are cross-resistant to a chemical carcinogen, benzo(a)pyrene, due to its cellular efflux by the P-gp-mediated putative drug efflux pump. Benzo(a)pyrene 118-132 ATP binding cassette subfamily B member 1 Homo sapiens 168-172 16647797-0 2006 Effect of benzo[a]pyrene on P-glycoprotein-mediated transport in Caco-2 cell monolayer. Benzo(a)pyrene 10-24 ATP binding cassette subfamily B member 1 Homo sapiens 28-42 9272928-1 1997 MDR1 P-glycoprotein (Pgp 170), a member of the adenosine triphosphate (ATP) binding cassette transporters, acts as an efflux pump for various hydrophobic agents, particularly for xenobiotics such as benzo(a)pyrene. Benzo(a)pyrene 199-213 ATP binding cassette subfamily B member 1 Homo sapiens 0-4 9272928-1 1997 MDR1 P-glycoprotein (Pgp 170), a member of the adenosine triphosphate (ATP) binding cassette transporters, acts as an efflux pump for various hydrophobic agents, particularly for xenobiotics such as benzo(a)pyrene. Benzo(a)pyrene 199-213 ATP binding cassette subfamily B member 1 Homo sapiens 5-19 17408918-0 2007 Effects of benzo(e)pyrene and benzo(a)pyrene on P-glycoprotein-mediated transport in Caco-2 cell monolayer: a comparative approach. Benzo(a)pyrene 30-44 ATP binding cassette subfamily B member 1 Homo sapiens 48-62 17408918-1 2007 The previous studies from our laboratory reported that benzo(a)pyrene (Bap) influenced efflux transport of rhodamine 123 (Rho-123) by induction of P-glycoprotein (P-gp) in Caco-2 cells. Benzo(a)pyrene 55-69 ATP binding cassette subfamily B member 1 Homo sapiens 147-161 17408918-1 2007 The previous studies from our laboratory reported that benzo(a)pyrene (Bap) influenced efflux transport of rhodamine 123 (Rho-123) by induction of P-glycoprotein (P-gp) in Caco-2 cells. Benzo(a)pyrene 55-69 ATP binding cassette subfamily B member 1 Homo sapiens 163-167 17408918-1 2007 The previous studies from our laboratory reported that benzo(a)pyrene (Bap) influenced efflux transport of rhodamine 123 (Rho-123) by induction of P-glycoprotein (P-gp) in Caco-2 cells. Benzo(a)pyrene 71-74 ATP binding cassette subfamily B member 1 Homo sapiens 147-161 17408918-1 2007 The previous studies from our laboratory reported that benzo(a)pyrene (Bap) influenced efflux transport of rhodamine 123 (Rho-123) by induction of P-glycoprotein (P-gp) in Caco-2 cells. Benzo(a)pyrene 71-74 ATP binding cassette subfamily B member 1 Homo sapiens 163-167 17408918-8 2007 Our results further show that Bep or Bap-induced P-gp in Caco-2 cells might have been the result of oxidative stress rather than DNA damage. Benzo(a)pyrene 37-40 ATP binding cassette subfamily B member 1 Homo sapiens 49-53