PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 8374053-2 1993 Substitution of BP at C-6 with fluorine to form 6-fluorobenzo[a]pyrene (6-FBP) or a methyl group to form 6-methylbenzo[a]pyrene (6-CH3BP) decreases tumorigenicity compared to BP. Benzo(a)pyrene 16-18 far upstream element binding protein 1 Rattus norvegicus 74-77 8374053-3 1993 BP, 6-FBP, and 6-CH3BP formed adducts with DNA when (1) they were activated by 3-methylcholanthrene-induced rat liver microsomes, (2) they were activated by horseradish peroxidase (HRP), (3) their 7,8-dihydrodiols were activated by microsomes, or (4) the radical cation of BP, 6-FBP, or 6-CH3-BP was directly reacted with DNA. Benzo(a)pyrene 0-2 far upstream element binding protein 1 Rattus norvegicus 279-282