PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
30006417-7	2018	CONCLUSIONS: Intensive BP lowering was associated with a mortality benefit only if declines in eGFR were <20%.	Benzo(a)pyrene	23-25	epidermal growth factor receptor	Homo sapiens	95-99	
12054747-3	2002	Immunocytochemistry and Western immunoblot analysis showed that BaP, but not TCDD, produced a marked loss of plasma membrane epidermal growth factor receptor (EGF-R) localized along intercellular boundaries.	Benzo(a)pyrene	64-67	epidermal growth factor receptor	Homo sapiens	125-157	
12054747-3	2002	Immunocytochemistry and Western immunoblot analysis showed that BaP, but not TCDD, produced a marked loss of plasma membrane epidermal growth factor receptor (EGF-R) localized along intercellular boundaries.	Benzo(a)pyrene	64-67	epidermal growth factor receptor	Homo sapiens	159-164	
7689475-1	1993	We demonstrate that blockage of EGF receptor signal transduction is sufficient by itself to cause a rapid, efficient, and reversible G0-like growth arrest of normal human mammary epithelial cells (HMEC) of finite lifespan as well as two immortally transformed cell lines derived from normal HMEC following in vitro transformation with benzo[a]pyrene.	Benzo(a)pyrene	335-349	epidermal growth factor receptor	Homo sapiens	32-44	
34991250-5	2022	Exposure to benzo(a)pyrene (B(a)P) and dioxin-like polychlorinated biphenyl (PCB) 126 resulted in a rapid c-Src-mediated phosphorylation of EGFR.	Benzo(a)pyrene	12-26	epidermal growth factor receptor	Homo sapiens	140-144	
34991250-5	2022	Exposure to benzo(a)pyrene (B(a)P) and dioxin-like polychlorinated biphenyl (PCB) 126 resulted in a rapid c-Src-mediated phosphorylation of EGFR.	Benzo(a)pyrene	28-33	epidermal growth factor receptor	Homo sapiens	140-144	
2154666-1	1990	Studies investigated the effects of benzo(a)pyrene (BP) treatment on epidermal growth factor (EGF) receptor binding and kinase activity in human placental cell cultures.	Benzo(a)pyrene	36-50	epidermal growth factor receptor	Homo sapiens	69-107	
2154666-1	1990	Studies investigated the effects of benzo(a)pyrene (BP) treatment on epidermal growth factor (EGF) receptor binding and kinase activity in human placental cell cultures.	Benzo(a)pyrene	52-54	epidermal growth factor receptor	Homo sapiens	69-107	
28247504-3	2017	Co-treatment with 5 microM BaP and 20 microM EGCG in BEAS-2B promoted a significant reduction in cell viability and greater G2/M cell cycle arrest, induction of ROS, and reductions in BaP-induced CYP1A1/CYP1B1/COMT, EGFR, p-Akt (Ser473), p-p53 (Thr55), and survivin mRNA/protein expression, as well as an increase in p-p53 (Ser15).	Benzo(a)pyrene	27-30	epidermal growth factor receptor	Homo sapiens	216-220	
28473636-8	2017	Thus, acute eGFR declines >=20% during intensive BP lowering identified a subset of patients at higher risk for adverse outcomes.	Benzo(a)pyrene	52-54	epidermal growth factor receptor	Homo sapiens	12-16	
28356338-0	2017	Time-Varying Association of Individual BP Components with eGFR in Late-Stage CKD.	Benzo(a)pyrene	39-41	epidermal growth factor receptor	Homo sapiens	58-62	
28356338-1	2017	BACKGROUND AND OBJECTIVES: The association of individual BP components with changes in eGFR in patients with late-stage CKD is unknown.	Benzo(a)pyrene	57-59	epidermal growth factor receptor	Homo sapiens	87-91	
28356338-5	2017	The associations of BP components and eGFR decline >=30% were examined with time-varying Cox models.	Benzo(a)pyrene	20-22	epidermal growth factor receptor	Homo sapiens	38-42	
22776036-11	2012	Independent determinants of CKD-eGFR <60 were increasing age at diabetes diagnosis, diabetes duration, total cholesterol and systolic BP.	Benzo(a)pyrene	137-139	epidermal growth factor receptor	Homo sapiens	32-36	
28260342-2	2017	Methods: This study, we firstly utilized immunofluorescence assay and Western-blot to examine EGFR expression of the BaP which was constructed previously by project team induced malignant transformation human bronchial epithelial cell (BTC) and the control (16HBE cell).	Benzo(a)pyrene	117-120	epidermal growth factor receptor	Homo sapiens	94-98	
26482258-11	2015	Associations between BP and both renal end point and rate of eGFR decline were similar to those with the primary end point.	Benzo(a)pyrene	21-23	epidermal growth factor receptor	Homo sapiens	61-65	
23746685-8	2013	There was a continuous relationship between BP and renal risk, with a significative risk of pathological albuminuria (OR=7.75 [6.69-8.96]) and of low eGFR (OR: 1.33 [1.09-1.60]) in subjects with BP greater than or equal to 180/110 mmHg, compared to those with normal BP.	Benzo(a)pyrene	44-46	epidermal growth factor receptor	Homo sapiens	150-154	
19686443-9	2010	Acute rejection, BP medications, and hospitalizations in prior six months had negative association with subsequent eGFR.	Benzo(a)pyrene	17-19	epidermal growth factor receptor	Homo sapiens	115-119	
19181443-0	2009	Benzo[a]pyrene promotes proliferation of human lung cancer cells by accelerating the epidermal growth factor receptor signaling pathway.	Benzo(a)pyrene	0-14	epidermal growth factor receptor	Homo sapiens	85-117