PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
17403528-2	2007	The GSTM1 null allele was associated with significantly higher levels of two biomarkers, malondialdehyde-2"-deoxyguanosine and benzo[a]pyrene DNA adducts in the total population from three Central and Eastern European countries.	Benzo(a)pyrene	127-141	glutathione S-transferase mu 1	Homo sapiens	4-9	
12507920-0	2002	CYP1A1 and GSTM1 genotypes affect benzo[a]pyrene DNA adducts in smokers" lung: comparison with aromatic/hydrophobic adduct formation.	Benzo(a)pyrene	34-48	glutathione S-transferase mu 1	Homo sapiens	11-16	
15036119-10	2004	Multiple linear regression analysis showed that the increase in anti-BPDE-DNA adduct levels in LMF was significantly related to the high occupational exposure to PAHs (benzo[a]pyrene (BaP)) of coke-oven workers (t = 3.087, P < 0.01) and to the lack of GSTM1 activity (t = 3.512, P < 0.001), rather than to the two other confounding factors of PAH intake, i.e. charcoal-broiled meat consumption and smoking habits.	Benzo(a)pyrene	184-187	glutathione S-transferase mu 1	Homo sapiens	255-260	
11164984-2	2001	The aim of this study was to elucidate the role of the GSTM1 genotype in protection against oxidant chemicals by comparing the sensitivity, genotoxicity and cytotoxicity of lymphocytes to benzo(a)pyrene (BaP)- and cumene hydroperoxide (CumOOH)-induced in vitro oxidative challenge.	Benzo(a)pyrene	188-202	glutathione S-transferase mu 1	Homo sapiens	55-60	
11164984-2	2001	The aim of this study was to elucidate the role of the GSTM1 genotype in protection against oxidant chemicals by comparing the sensitivity, genotoxicity and cytotoxicity of lymphocytes to benzo(a)pyrene (BaP)- and cumene hydroperoxide (CumOOH)-induced in vitro oxidative challenge.	Benzo(a)pyrene	204-207	glutathione S-transferase mu 1	Homo sapiens	55-60	
11164984-4	2001	Following supplementation with BaP or CumOOH, time-dependent increases were observed in the production of all the markers after incubation for 12-48 h. However, we could not find any differences between GSTM1 null and positive genotypes.	Benzo(a)pyrene	31-34	glutathione S-transferase mu 1	Homo sapiens	203-208	
11164984-5	2001	Furthermore, dose or time response experiments indicated that GSTM1-deficient cells were not more sensitive than control cells to BaP-or CumOOH-induced cell killing and micronucleus formation, although they were hypersensitive to BaP-inhibited cellular growth.	Benzo(a)pyrene	230-233	glutathione S-transferase mu 1	Homo sapiens	62-67	
10385146-2	1999	Glutathione S-transferase M1 (GSTM1) detoxifies benzo(a)pyrene and other carcinogens in tobacco smoke.	Benzo(a)pyrene	48-62	glutathione S-transferase mu 1	Homo sapiens	0-28	
11201055-0	2000	Inhibition of platelet function by GSTM1-null human peripheral lymphocytes exposed to benzo(a)pyrene-induced challenge.	Benzo(a)pyrene	86-100	glutathione S-transferase mu 1	Homo sapiens	35-40	
11201055-8	2000	However, our results indicate that lymphocytes of individuals with the GSTM1-null genotype have greater inhibitory activity on platelet function after exposure to BaP, but not CumOOH, although they are not more susceptible to in vitro oxidative stress.	Benzo(a)pyrene	163-166	glutathione S-transferase mu 1	Homo sapiens	71-76	
10385146-2	1999	Glutathione S-transferase M1 (GSTM1) detoxifies benzo(a)pyrene and other carcinogens in tobacco smoke.	Benzo(a)pyrene	48-62	glutathione S-transferase mu 1	Homo sapiens	30-35	
21528215-1	1997	Cytochrome p4501A1 gene (CYP1A1) and glutathione S-transferase mu gene (GSTM1) are involved in the metabolic activation or detoxification of environmental carcinogens including benzo[a]pyrene in tobacco smoke.	Benzo(a)pyrene	177-191	glutathione S-transferase mu 1	Homo sapiens	72-77	
26197327-10	2015	Moreover, an association was found between GSTM1 null and alterations related to BP, but we did not observe any effects of other polymorphisms.	Benzo(a)pyrene	81-83	glutathione S-transferase mu 1	Homo sapiens	43-48	
35193440-0	2022	Alterations of DNA methylation and mRNA levels of CYP1A1, GSTP1, and GSTM1 in human bronchial epithelial cells induced by benzo(a)pyrene.	Benzo(a)pyrene	122-136	glutathione S-transferase mu 1	Homo sapiens	69-74	
35193440-6	2022	The mRNA levels of CYP1A1, GSTP1, and GSTM1 were significantly decreased in 16HBEs following B(a)P treatment at all three doses.	Benzo(a)pyrene	93-98	glutathione S-transferase mu 1	Homo sapiens	38-43	
35065163-7	2022	The highest amount of COX-2, the most increased activity of CYP1A1 and cPLA2, and overexpression of GSTM1, CYP1A1, ICAM-1, and VCAM-1 gene was observed in HUVEC cells treated with BaP.	Benzo(a)pyrene	180-183	glutathione S-transferase mu 1	Homo sapiens	100-105	
35065163-8	2022	After co-treatment with BaP and ARA or EPA, an increase of GSTM1 level was observed.	Benzo(a)pyrene	24-27	glutathione S-transferase mu 1	Homo sapiens	59-64	
27362771-6	2016	Repressesion of COX-2, cPGES and overexpressesion of GSTM1 protein was noted after co-treatment with RvD1 and BaP.	Benzo(a)pyrene	110-113	glutathione S-transferase mu 1	Homo sapiens	53-58