PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
25855778-7	2015	These findings suggest that direct actions of AT1A receptors in VSMCs are essential for regulation of renal blood flow by Ang II and highlight the capacity of Ang II-dependent vascular responses in the kidney to effect natriuresis and BP control.	Benzo(a)pyrene	235-237	angiotensinogen (serpin peptidase inhibitor, clade A, member 8)	Mus musculus	159-165	
25855778-0	2015	Vascular Type 1A Angiotensin II Receptors Control BP by Regulating Renal Blood Flow and Urinary Sodium Excretion.	Benzo(a)pyrene	50-52	angiotensinogen (serpin peptidase inhibitor, clade A, member 8)	Mus musculus	17-31	
23676189-13	2014	CONCLUSIONS: BaP promotes Ang II-induced AAA formation in mice via elevating infiltration of macrophages, activating nuclear factor-kappaB, upregulating the expression of MMP-2, MMP-9, and MMP-12, and increasing the apoptosis of vascular muscle cells in its synergistic effect with Ang II in aortic wall.	Benzo(a)pyrene	13-16	angiotensinogen (serpin peptidase inhibitor, clade A, member 8)	Mus musculus	26-32	
23676189-0	2014	Exploration of the mechanisms by which 3,4-benzopyrene promotes angiotensin II-induced abdominal aortic aneurysm formation in mice.	Benzo(a)pyrene	39-54	angiotensinogen (serpin peptidase inhibitor, clade A, member 8)	Mus musculus	64-78	
23676189-1	2014	OBJECTIVE: This study examined the influence of 3,4-benzopyrene (BaP), a compound found in cigarette smoke, on the formation of angiotensin II (Ang II)-induced abdominal aortic aneurysm (AAA) formation in mice and the underlying mechanisms.	Benzo(a)pyrene	48-63	angiotensinogen (serpin peptidase inhibitor, clade A, member 8)	Mus musculus	128-142	
23676189-1	2014	OBJECTIVE: This study examined the influence of 3,4-benzopyrene (BaP), a compound found in cigarette smoke, on the formation of angiotensin II (Ang II)-induced abdominal aortic aneurysm (AAA) formation in mice and the underlying mechanisms.	Benzo(a)pyrene	48-63	angiotensinogen (serpin peptidase inhibitor, clade A, member 8)	Mus musculus	144-150	
23676189-1	2014	OBJECTIVE: This study examined the influence of 3,4-benzopyrene (BaP), a compound found in cigarette smoke, on the formation of angiotensin II (Ang II)-induced abdominal aortic aneurysm (AAA) formation in mice and the underlying mechanisms.	Benzo(a)pyrene	65-68	angiotensinogen (serpin peptidase inhibitor, clade A, member 8)	Mus musculus	128-142	
23676189-1	2014	OBJECTIVE: This study examined the influence of 3,4-benzopyrene (BaP), a compound found in cigarette smoke, on the formation of angiotensin II (Ang II)-induced abdominal aortic aneurysm (AAA) formation in mice and the underlying mechanisms.	Benzo(a)pyrene	65-68	angiotensinogen (serpin peptidase inhibitor, clade A, member 8)	Mus musculus	144-150	
23676189-9	2014	RESULTS: The Ang II infusion and BaP injection induced AAAs in 41.67% of mice vs 25% in the Ang II group (P < .05).	Benzo(a)pyrene	33-36	angiotensinogen (serpin peptidase inhibitor, clade A, member 8)	Mus musculus	92-98	
23676189-13	2014	CONCLUSIONS: BaP promotes Ang II-induced AAA formation in mice via elevating infiltration of macrophages, activating nuclear factor-kappaB, upregulating the expression of MMP-2, MMP-9, and MMP-12, and increasing the apoptosis of vascular muscle cells in its synergistic effect with Ang II in aortic wall.	Benzo(a)pyrene	13-16	angiotensinogen (serpin peptidase inhibitor, clade A, member 8)	Mus musculus	282-288	
16371432-8	2006	Aortae of mice treated with Ang II antagonism had fewer elastin breaks together with less immunostaining for the powerful elastolytic enzyme cathepsin S. None of these benefits was observed in the hydralazine-treated mice despite equivalent reduction in BP.	Benzo(a)pyrene	254-256	angiotensinogen (serpin peptidase inhibitor, clade A, member 8)	Mus musculus	28-34	
22021713-3	2011	After 14 days, AngII increased both BP and the numbers of CD3(+) and proliferating cells in the kidney.	Benzo(a)pyrene	36-38	angiotensinogen (serpin peptidase inhibitor, clade A, member 8)	Mus musculus	15-20	
22021713-7	2011	Taken together, these data suggest that ET(A) receptor activation in AngII-mediated hypertension increases CD3(+) cells and proliferation in the renal cortex independent of changes in BP, but changes in the number of inflammatory cells in the renal medulla are BP dependent.	Benzo(a)pyrene	261-263	angiotensinogen (serpin peptidase inhibitor, clade A, member 8)	Mus musculus	69-74