PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
30270567-9	2019	The daily insulin dosage among GLP-1RA/insulin users was 30.3 IU/day (95% CI, -41.2 to -19.3; P < 0.001; I2  = 94%), lower than with BP/BB.	Benzo(a)pyrene	136-138	insulin	Homo sapiens	10-17	
3266252-3	1988	In a multiple linear (step-wise) regression analysis, body mass index, age, immunoreactive insulin two hours after glucose load and serum total cholesterol contributed directly to the BP value but the weekly ethanol intake did not.	Benzo(a)pyrene	184-186	insulin	Homo sapiens	91-98	
19808042-6	2010	Uncharged tRNA inhibit GTP exchange on eIF2, and free amino acids and insulin inhibit reversible sequestration of F4e by Bp.	Benzo(a)pyrene	121-123	insulin	Homo sapiens	70-77	
26522487-8	2015	Five-year weight changes associate with BP alterations, even after adjustment for changes in lifestyle risk factors and serum insulin.	Benzo(a)pyrene	40-42	insulin	Homo sapiens	126-133	
19236443-12	2009	Improvements in the insulin delivery technique might allow to optimize drug application in all cases with even higher BA/BP with RHIIP.	Benzo(a)pyrene	121-123	insulin	Homo sapiens	20-27	
16126119-13	2005	These findings indicate firstly that RSG is able to induce a reduction of BP and secondly the amelioration of insulin sensitivity is associated with the reduction of BP.	Benzo(a)pyrene	166-168	insulin	Homo sapiens	110-117	
8432415-3	1993	Recent investigations have shown racial differences in the relationship between insulin resistance and BP in nondiabetic populations.	Benzo(a)pyrene	103-105	insulin	Homo sapiens	80-87	
9683191-0	1998	Benzo[a]pyrene- and TCDD-induced alterations in tyrosine phosphorylation and insulin-like growth factor signaling pathways in the MCF-10A human mammary epithelial cell line.	Benzo(a)pyrene	0-14	insulin	Homo sapiens	77-84	
9683191-3	1998	In the present studies we found that BaP and TCDD activated insulin-like growth factor (IGF-I) signaling pathways under insulin-deficient conditions.	Benzo(a)pyrene	37-40	insulin	Homo sapiens	60-67	
7671346-0	1995	Inhibition of benzo[a]pyrene metabolism by insulin, FITC-insulin and an FITC-insulin-antibody conjugate in the human hepatoma cell line HepG2.	Benzo(a)pyrene	14-28	insulin	Homo sapiens	43-50	
9683191-5	1998	BaP (0.3 microM) and TCDD (30 nM) were found to restore a moderate insulin-like signal in MCF-10A cells grown in the absence of added insulin.	Benzo(a)pyrene	0-3	insulin	Homo sapiens	67-74	
7671346-4	1995	Metabolism of BaP to water-soluble metabolites by HepG2 cells in culture was 50% lower in fluorescein isothiocyanate (FITC)-insulin-CYP1A1-antibody-conjugate-treated cells than in control cells.	Benzo(a)pyrene	14-17	insulin	Homo sapiens	124-131	
7671346-5	1995	However, FITC-insulin (lacking anti CYP1A1 conjugates) or insulin alone also decreased BaP metabolism by 50%.	Benzo(a)pyrene	87-90	insulin	Homo sapiens	14-21	
7671346-5	1995	However, FITC-insulin (lacking anti CYP1A1 conjugates) or insulin alone also decreased BaP metabolism by 50%.	Benzo(a)pyrene	87-90	insulin	Homo sapiens	58-65	
7671346-6	1995	This insulin-induced inhibition of BaP metabolism was observed for cultures treated with a concentration range of FITC-insulin from 50-1000 nM.	Benzo(a)pyrene	35-38	insulin	Homo sapiens	5-12	
7671346-6	1995	This insulin-induced inhibition of BaP metabolism was observed for cultures treated with a concentration range of FITC-insulin from 50-1000 nM.	Benzo(a)pyrene	35-38	insulin	Homo sapiens	119-126	
7671346-8	1995	These results demonstrate that free insulin, FITC-insulin or FITC-insulin conjugated to antibodies are effective inhibitors of BaP metabolism in cells in culture.	Benzo(a)pyrene	127-130	insulin	Homo sapiens	36-43	
1956022-12	1991	Insulin resistance and compensatory hyperinsulinaemia might lead to an increase in BP by a number of putative mechanisms, such as enhancing renal sodium retention, by an effect on cell membrane ion exchange mechanisms or by enhancing activity of the sympathetic nervous system.	Benzo(a)pyrene	83-85	insulin	Homo sapiens	0-7	
1464889-1	1992	The purpose of this study was to examine the relationship between insulin and BP in patients with normal glucose tolerance.	Benzo(a)pyrene	78-80	insulin	Homo sapiens	66-73