PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 23834963-0 2013 P-glycoprotein and CYP1A protein expression patterns in Nile tilapia (Oreochromis niloticus) tissues after waterborne exposure to benzo(a)pyrene (BaP). Benzo(a)pyrene 146-149 cytochrome P450 1A Oreochromis niloticus 19-24 23834963-0 2013 P-glycoprotein and CYP1A protein expression patterns in Nile tilapia (Oreochromis niloticus) tissues after waterborne exposure to benzo(a)pyrene (BaP). Benzo(a)pyrene 130-144 cytochrome P450 1A Oreochromis niloticus 19-24 23834963-4 2013 CYP1A, detected with the mAb C10-7, reacted positively in liver, gills and intestine and followed a BaP dose-dependent fold induction. Benzo(a)pyrene 100-103 cytochrome P450 1A Oreochromis niloticus 0-5 23834963-5 2013 Taken together, these results indicate that CYP1A is involved in BaP metabolism in liver, gills and intestine, however, further studies are needed to elucidate the possible interaction of the efflux protein Pgp with BaP and/or its metabolites. Benzo(a)pyrene 65-68 cytochrome P450 1A Oreochromis niloticus 44-49 23834963-5 2013 Taken together, these results indicate that CYP1A is involved in BaP metabolism in liver, gills and intestine, however, further studies are needed to elucidate the possible interaction of the efflux protein Pgp with BaP and/or its metabolites. Benzo(a)pyrene 216-219 cytochrome P450 1A Oreochromis niloticus 44-49 22227637-0 2012 Gene expression analysis of ABC efflux transporters, CYP1A and GSTalpha in Nile tilapia after exposure to benzo(a)pyrene. Benzo(a)pyrene 106-120 cytochrome P450 1A Oreochromis niloticus 53-58 23597728-5 2013 BaP-induced CYP1A mRNA levels were unaffected by hypoxia, suggesting that reduced bile BaP concentration may be related with effects on protein amount or enzyme activities. Benzo(a)pyrene 0-3 cytochrome P450 1A Oreochromis niloticus 12-17 22227637-1 2012 The aim of this study was to evaluate the response of ABC transporters, CYP1A and class alpha (alpha) GST genes, upon water and dietary exposures to benzo(a)pyrene (BaP) in Oreochromis niloticus. Benzo(a)pyrene 149-163 cytochrome P450 1A Oreochromis niloticus 72-77 22227637-1 2012 The aim of this study was to evaluate the response of ABC transporters, CYP1A and class alpha (alpha) GST genes, upon water and dietary exposures to benzo(a)pyrene (BaP) in Oreochromis niloticus. Benzo(a)pyrene 165-168 cytochrome P450 1A Oreochromis niloticus 72-77 22227637-7 2012 In conclusion, this study has shown that transcriptional expression of some ABC transporters and CYP1A respond to the presence of BaP, indicating a possible involvement and cooperation in the detoxification process in Nile tilapia. Benzo(a)pyrene 130-133 cytochrome P450 1A Oreochromis niloticus 97-102