PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
15837074-0	2005	Benzo[a]pyrene, but not 2,3,7,8-TCDD, induces G2/M cell cycle arrest, p21CIP1 and p53 phosphorylation in human choriocarcinoma JEG-3 cells: a distinct signaling pathway.	Benzo(a)pyrene	0-14	cyclin dependent kinase inhibitor 1A	Homo sapiens	70-77	
21887816-6	2013	Pretreatment with cytochrome P450 inhibitor alpha-naphthoflavone or p53 inhibitor pifithrin-alpha inhibited the benzo-[a]-pyrene-induced p21 expression.	Benzo(a)pyrene	112-128	cyclin dependent kinase inhibitor 1A	Homo sapiens	137-140	
24868967-0	2014	[Roles of p53 in the interaction of p21 and cell cycle proteins induced by benzo [a] pyrene].	Benzo(a)pyrene	75-91	cyclin dependent kinase inhibitor 1A	Homo sapiens	36-39	
24868967-1	2014	OBJECTIVE: To investigate the roles of p53 in the interaction of p21, cyclin D1 and CDK4 in human embryonic lung fibroblasts (HELFs) induced by benzo (a) pyrene.	Benzo(a)pyrene	144-160	cyclin dependent kinase inhibitor 1A	Homo sapiens	65-68	
23678290-5	2013	When these isogenic cell lines are treated with BP for 48 h, accumulation of G2M phase and aneuploidy are commonly observed, and HCT116 p21(-) cells show increase in apoptosis.	Benzo(a)pyrene	48-50	cyclin dependent kinase inhibitor 1A	Homo sapiens	136-139	
23678290-6	2013	In xenograft assay, s.c. injection of BP efficiently inhibits tumorigenesis of HCT116 deficient for Chk2 or p21.	Benzo(a)pyrene	38-40	cyclin dependent kinase inhibitor 1A	Homo sapiens	108-111	
23678290-9	2013	These results demonstrate that p21 deficiency enhances BP-mediated suppression of tumor growth, and that BP and 5-FU can collaborate for tumor regression.	Benzo(a)pyrene	55-57	cyclin dependent kinase inhibitor 1A	Homo sapiens	31-34