PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
23036591-16	2012	Exposure to BaP affected mo-DC function as demonstrated by decreased IL6 expression induced by PolyI:C, without affecting indoleamine 2,3 dioxygenase (IDO)1 expression.	Benzo(a)pyrene	12-15	interleukin 6	Homo sapiens	69-72	
25174381-18	2014	Compared with those detected before treatment, the levels of TNF-alpha, IL-6, and IL-8 in serum of group BP at PTH 24 and 48 were significantly decreased (with P values below 0.01).	Benzo(a)pyrene	105-107	interleukin 6	Homo sapiens	72-76	
31323583-7	2019	We found that DEHP at the indicated concentration plus 50.00muM BaP increased cellular and mitochondrial ROS levels, IL-6 and IL-8 secretions at 24 and 48h as well as MDA levels and GSH-Px activities at 48h, compared to the solvent control.	Benzo(a)pyrene	64-67	interleukin 6	Homo sapiens	117-121	
16002475-6	2005	Induction of IL-1alpha, IL-6, IL-11, and FGF-9 mRNA by MEP and benzo(a)pyrene was concentration and time dependent.	Benzo(a)pyrene	63-77	interleukin 6	Homo sapiens	24-28	
16002475-8	2005	Treatment with MEP or benzo(a)pyrene increased IL-6 and IL-11 releases to CL5 cell medium.	Benzo(a)pyrene	22-36	interleukin 6	Homo sapiens	47-51	
15901049-5	2005	Significantly decreased concentrations of beta2-MG, IL-6 and total protein were found in both BAP and BP.	Benzo(a)pyrene	102-104	interleukin 6	Homo sapiens	52-56	
10915744-5	2000	Four- and 10-fold activation of stress protein was detected by a consensus heat shock factor (HSF) sequence binding probe, with AFB and BP treatments, respectively.	Benzo(a)pyrene	136-138	interleukin 6	Homo sapiens	75-92	
10915744-5	2000	Four- and 10-fold activation of stress protein was detected by a consensus heat shock factor (HSF) sequence binding probe, with AFB and BP treatments, respectively.	Benzo(a)pyrene	136-138	interleukin 6	Homo sapiens	94-97	
2236903-2	1990	Single organic- and water-soluble metabolites increased with BaP concentration in both types of HSF, but the ratio normal/variant increased with BaP concentration.	Benzo(a)pyrene	61-64	interleukin 6	Homo sapiens	96-99	
6440265-6	1984	This behavior of G6PD-deficient HL and HSF is coupled with an increase of the resistance to the cell death induced by benzo(a)pyrene (BP).	Benzo(a)pyrene	118-132	interleukin 6	Homo sapiens	39-42	
6440265-6	1984	This behavior of G6PD-deficient HL and HSF is coupled with an increase of the resistance to the cell death induced by benzo(a)pyrene (BP).	Benzo(a)pyrene	134-136	interleukin 6	Homo sapiens	39-42	
31515600-5	2019	The objective of this work was to investigate the molecular toxicology and local activation of BaP and PhIP in the presence of IL-6.	Benzo(a)pyrene	95-98	interleukin 6	Homo sapiens	127-131	
31515600-12	2019	These data show that BaP- and PhIP-induced DNA damage in mammary cells is potentiated by the inflammatory cytokine IL-6 and that inflammation-induced CYP expression, specifically CYP1B1 via miR27b, is responsible for this effect.	Benzo(a)pyrene	21-24	interleukin 6	Homo sapiens	115-119	
26609631-4	2016	Here, we show that benzo[a]pyrene diol epoxide (BPDE, the active metabolite of cigarette smoke carcinogen benzo[a]pyrene)-induced human bronchial epithelial cell (HBEC) transformation was enhanced by IL-6 in vitro.	Benzo(a)pyrene	19-33	interleukin 6	Homo sapiens	200-204	
31387194-6	2019	BP up-regulated anti-oxidant (NQO1, Txnrd1, Nrf2) and down-regulated inflammatory (TNF-alpha and IL-6) mRNA expressions, in accompany with MAPK signaling inhibition.	Benzo(a)pyrene	0-2	interleukin 6	Homo sapiens	97-101	
30758933-5	2019	On this coculture model, 2D bP may increase anti-inflammatory cytokine generation (i.e., interleukin-10) and inhibit proinflammatory mediators synthesis (i.e., interleukin-6), thus suggesting the opportunity to prevent cancer-related inflammation.	Benzo(a)pyrene	28-30	interleukin 6	Homo sapiens	160-173	
29320557-10	2018	Two well-known ligands for AHR (TCDD and BaP) induced mRNA expression of IL1B and IL6 in an ERalpha-negative breast tumor cell line.	Benzo(a)pyrene	41-44	interleukin 6	Homo sapiens	82-85	
28914726-10	2018	From pretreatment to posttreatment, CBTI-BP compared with psychoeducation was associated with a nonsignificant, large effect size decrease in IL-6 (z = -1.61, p = .13, d = -0.78) and a nonsignificant, small-medium effect size decrease in sTNF-R2 (z = -0.79, p = .44, d = -0.38).	Benzo(a)pyrene	41-43	interleukin 6	Homo sapiens	142-146	
26963242-0	2016	Benzo(a)pyrene induces interleukin (IL)-6 production and reduces lipid synthesis in human SZ95 sebocytes via the aryl hydrocarbon receptor signaling pathway.	Benzo(a)pyrene	0-14	interleukin 6	Homo sapiens	23-41