PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
31705795-6	2020	Under excess glucose conditions, allopurinol significantly inhibited trophoblast secretion of inflammatory IL-1beta; caspase-1 activity; IL-8; RANTES; and GRO-alpha.	Allopurinol	33-44	C-X-C motif chemokine ligand 8	Homo sapiens	137-141	
33456597-9	2020	Addition of synbiotic to allopurinol leads to a blood uric acid lowering (18.7% vs. 13.3%, p <0.01), CRP reduction (75% vs. 26.3%, p <0.01) as well as decrease of cytokines level: IL-1beta, IL-6, IL-8, IL-10 and TNFalpha (all p <0.001).	Allopurinol	25-36	C-X-C motif chemokine ligand 8	Homo sapiens	196-200	
27894951-0	2017	A pilot study of CXCL8 levels in crystal proven gout patients during allopurinol treatment and their association with cardiovascular disease.	Allopurinol	69-80	C-X-C motif chemokine ligand 8	Homo sapiens	17-22	
27894951-3	2017	We hypothesized that the well-known cardiovascular protective effects of allopurinol could be related to effects of this drug on CXCL8 levels.	Allopurinol	73-84	C-X-C motif chemokine ligand 8	Homo sapiens	129-134	
26641773-4	2016	In this study, we demonstrate that treatment of HL-60 cells with allopurinol significantly increased the mRNA expression levels of interleukin-8, monocyte chemotactic protein-1 and tumor necrosis factor alpha in a time- and concentration-dependent manner.	Allopurinol	65-76	C-X-C motif chemokine ligand 8	Homo sapiens	131-144