PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
10553245-8	1999	For instance, when comparing proteins that inhibit calcium phosphate precipitation, statherin and acidic proline-rich proteins are most potent, whereas histatins, cystatins, and mucins appear to play lesser roles.	calcium phosphate	51-68	statherin	Homo sapiens	84-93	
18266360-1	2008	Statherin is an active inhibitor of calcium phosphate precipitation in the oral cavity.	calcium phosphate	36-53	statherin	Homo sapiens	0-9	
15892946-3	2005	The proposed function of those that are multiphosphorylated is: (i) the stabilisation of calcium phosphate in solution (e.g. casein, statherin) preventing spontaneous precipitation and seeded-crystal growth or (ii) promoting biomineralisation (e.g. the phosphophoryn domain of DSPP), where the protein described as a template macromolecule, is proposed to act as a nucleator/promoter of crystal growth.	calcium phosphate	89-106	statherin	Homo sapiens	133-142	
15725522-3	2005	The proline-rich proteins, statherin and the histatins are salivary proteins that influence calcium phosphate chemistry, initial plaque formation and candida infection.	calcium phosphate	92-109	statherin	Homo sapiens	27-36	
12060866-0	2002	Comparison of inhibitory activity on calcium phosphate precipitation by acidic proline-rich proteins, statherin, and histatin-1.	calcium phosphate	37-54	statherin	Homo sapiens	102-111	
12060866-1	2002	This study quantitatively compares the inhibition of calcium phosphate (CaP) precipitation by the salivary acidic proline-rich proteins (PRPs) statherin and histatin-1.	calcium phosphate	53-70	statherin	Homo sapiens	143-152	
1525706-0	1992	Inhibition of calcium phosphate precipitation by human salivary statherin: structure-activity relationships.	calcium phosphate	14-31	statherin	Homo sapiens	64-73	
9048421-0	1996	Solid-phase synthesis and characterization of human salivary statherin: a tyrosine-rich phosphoprotein inhibitor of calcium phosphate precipitation.	calcium phosphate	116-133	statherin	Homo sapiens	61-70	
1525706-1	1992	Previous studies of human statherin showed the active region for inhibition of secondary calcium phosphate precipitation (crystal growth) to reside in the highly charged amino-terminal one-third of this molecule, and the neutral tyrosine-, glutamine- and proline-rich carboxy-terminal two-thirds of the molecule is required for maximal inhibition of primary (spontaneous) precipitation.	calcium phosphate	89-106	statherin	Homo sapiens	26-35	
3679674-0	1987	Chemical synthesis of phosphoseryl-phosphoserine, a partial analogue of human salivary statherin, a protein inhibitor of calcium phosphate precipitation in human saliva.	calcium phosphate	121-138	statherin	Homo sapiens	87-96	
24700504-2	2014	Here, human salivary statherin-inspired genetically engineered recombinamers (ELRs, HSS) on biomedical surfaces regulates mineralization to form an amorphous-calcium-phosphate (ACP) layer that reproduces the original substrate nanotopography.	calcium phosphate	158-175	statherin	Homo sapiens	21-30	
2613439-0	1989	Complete primary structure of statherin, a potent inhibitor of calcium phosphate precipitation, from the saliva of the monkey, Macaca arctoides.	calcium phosphate	63-80	statherin	Homo sapiens	30-39	
3476566-2	1987	The major acidic proline-rich proteins and the proline-rich phosphopeptide, statherin, of man and macaques have been shown to be potent inhibitors of calcium phosphate precipitation and are thought to function in the oral environment by maintaining saliva supersaturated with respect to calcium phosphate salts.	calcium phosphate	150-167	statherin	Homo sapiens	76-85	
6429216-0	1984	Relationship between concentration of human salivary statherin and inhibition of calcium phosphate precipitation in stimulated human parotid saliva.	calcium phosphate	81-98	statherin	Homo sapiens	53-62	
3922899-9	1985	The latter reactions may manifest themselves in the inhibition of spontaneous precipitation of calcium phosphate; thus these polyols may mimic the function of innate inhibitors, statherin, for example.	calcium phosphate	95-112	statherin	Homo sapiens	178-187	
838735-0	1977	Complete covalent structure of statherin, a tyrosine-rich acidic peptide which inhibits calcium phosphate precipitation from human parotid saliva.	calcium phosphate	88-105	statherin	Homo sapiens	31-40	
838735-1	1977	The complete amino acid sequence of human salivary statherin, a peptide which strongly inhibits precipitation from supersaturated calcium phosphate solutions, and therefore stabilizes supersaturated saliva, has been determined.	calcium phosphate	130-147	statherin	Homo sapiens	51-60	
25466354-2	2015	Two calcium phosphate proteins, statherin (43 amino acids) and leucine rich amelogenin protein (LRAP; 59 amino acids), have been studied in depth and have different dynamic properties and 2D- and 3D-structural features.	calcium phosphate	4-21	statherin	Homo sapiens	32-41	
22899678-6	2012	These casein phosphopeptide-stabilized amorphous calcium phosphate nanocomplexes (CPP-ACP) can stabilize even higher concentrations of calcium and phosphate than milk and can be considered a salivary biomimetic, since they share many similarities to statherin.	calcium phosphate	49-66	statherin	Homo sapiens	250-259	
31837358-1	2020	OBJECTIVES: The objective of this study was to investigate enamel remineralization using salivary statherin protein-inspired poly(amidoamine) dendrimer (SN15-PAMAM) and adhesive containing nanoparticles of amorphous calcium phosphate (NACP) in a cyclic artificial saliva/demineralizing solution for the first time.	calcium phosphate	216-233	statherin	Homo sapiens	98-107	
28487820-0	2017	Recombinant DNA technology and click chemistry: a powerful combination for generating a hybrid elastin-like-statherin hydrogel to control calcium phosphate mineralization.	calcium phosphate	138-155	statherin	Homo sapiens	108-117	
28487820-5	2017	The recombinamer contains the SNA15 peptide domains inspired by salivary statherin, a peptide epitope known to specifically bind to and nucleate calcium phosphate.	calcium phosphate	145-162	statherin	Homo sapiens	73-82	
28487820-7	2017	Mineralization of the resulting hybrid elastin-like-statherin recombinamer hydrogels with calcium phosphate is described.	calcium phosphate	90-107	statherin	Homo sapiens	52-61	
28572822-2	2017	Salivary proteins such as statherin inhibit crystal growth of calcium phosphate in supersaturated solutions and interact with several oral bacteria to adsorb on hydroxyapatite.	calcium phosphate	62-79	statherin	Homo sapiens	26-35	
20731414-1	2010	Human salivary statherin inhibits both primary and secondary calcium phosphate precipitation and, upon binding to hydroxyapatite, associates with a variety of oral bacteria.	calcium phosphate	61-78	statherin	Homo sapiens	15-24	
20731414-9	2010	Whole saliva protease activities separated the charged N-terminus from the hydrophobic C-terminus, negatively impacting on full length statherin functions comprising enamel lubrication and inhibition of primary calcium phosphate precipitation.	calcium phosphate	211-228	statherin	Homo sapiens	135-144