PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
33512650-0	2021	Strong Binding of Leupeptin with TMPRSS2 Protease May Be an Alternative to Camostat and Nafamostat for SARS-CoV-2 Repurposed Drug: Evaluation from Molecular Docking and Molecular Dynamics Simulations.	leupeptin	18-27	transmembrane serine protease 2	Homo sapiens	33-40	
33512650-8	2021	The docking study reveals that leupeptin molecule strongly binds with TMPRSS2 protein than the other two drug molecules.	leupeptin	31-40	transmembrane serine protease 2	Homo sapiens	70-77	
33512650-10	2021	Furthermore, leupeptin forms interactions with the key amino acids of TMPRSS2 and the same have been maintained during the MD simulations.	leupeptin	13-22	transmembrane serine protease 2	Homo sapiens	70-77	
33512650-11	2021	This structural and dynamical information is useful to evaluate these drugs to be used as repurposed drugs, however, the strong binding profile of leupeptin with TMPRSS2, suggests, it may be considered as a repurposed drug for COVID-19 disease after clinical trial.	leupeptin	147-156	transmembrane serine protease 2	Homo sapiens	162-169