PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 15500931-5 2004 According to the Western blot analysis, DATS decreased cyclin-dependent kinase (Cdks)-Cdk7 (i.e. Cdc2 activate kinase) protein levels in J5 cells but increased cyclin B1 protein level. diallyl trisulfide 40-44 cyclin dependent kinase 7 Homo sapiens 86-90 15500931-6 2004 The modulation potency to cyclin B1 and Cdk7 expressions was in the order of DATS > DADS > DAS. diallyl trisulfide 77-81 cyclin dependent kinase 7 Homo sapiens 40-44 15500931-7 2004 The modulation potency to cyclin B1 and Cdk7 protein levels increased with increasing in DATS concentration and culture time. diallyl trisulfide 89-93 cyclin dependent kinase 7 Homo sapiens 40-44 15500931-8 2004 In conclusion, DATS might affect cell viability and cell morphological changes in J5 cells and lead cells to be arrested in G2/M phase via controlling the expression of cyclin B1 and Cdk7 in J5 cells, and the controlling action might relate to the sulfuric atom numbers in the structures of all these allyl sulfides. diallyl trisulfide 15-19 cyclin dependent kinase 7 Homo sapiens 183-187