PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 24489685-0 2014 Keap1 cysteine 288 as a potential target for diallyl trisulfide-induced Nrf2 activation. diallyl trisulfide 45-63 nuclear factor, erythroid derived 2, like 2 Mus musculus 72-76 28218609-4 2017 Treatment with DATS alone effectively upregulated the expression of nuclear factor-erythroid 2-related factor 2 (Nrf2) and thioredoxin reductase 1 (TrxR1), which was associated with the increased phosphorylation of Nrf2. diallyl trisulfide 15-19 nuclear factor, erythroid derived 2, like 2 Mus musculus 68-111 28218609-4 2017 Treatment with DATS alone effectively upregulated the expression of nuclear factor-erythroid 2-related factor 2 (Nrf2) and thioredoxin reductase 1 (TrxR1), which was associated with the increased phosphorylation of Nrf2. diallyl trisulfide 15-19 nuclear factor, erythroid derived 2, like 2 Mus musculus 113-117 28218609-4 2017 Treatment with DATS alone effectively upregulated the expression of nuclear factor-erythroid 2-related factor 2 (Nrf2) and thioredoxin reductase 1 (TrxR1), which was associated with the increased phosphorylation of Nrf2. diallyl trisulfide 15-19 nuclear factor, erythroid derived 2, like 2 Mus musculus 215-219 28218609-6 2017 Moreover, DATS-mediated phosphorylation of Nrf2 and induction of TrxR1 were markedly reduced by genetic silencing of Nrf2. diallyl trisulfide 10-14 nuclear factor, erythroid derived 2, like 2 Mus musculus 43-47 28218609-6 2017 Moreover, DATS-mediated phosphorylation of Nrf2 and induction of TrxR1 were markedly reduced by genetic silencing of Nrf2. diallyl trisulfide 10-14 nuclear factor, erythroid derived 2, like 2 Mus musculus 117-121 28218609-7 2017 DATS treatment also induced the phosphorylation extracellular signal-regulating kinase (ERK), and analysis using specific inhibitors of cellular signaling pathways demonstrated that only ERK activation was involved in Nrf2 phosphorylation and TrxR1 induction. diallyl trisulfide 0-4 nuclear factor, erythroid derived 2, like 2 Mus musculus 218-222 28218609-9 2017 The results demonstrate that DATS protects against oxidative stress-induced DNA damage and apoptosis in C2C12 cells in part through the activation of Nrf2-mediated TrxR1 induction via the ERK signaling pathway. diallyl trisulfide 29-33 nuclear factor, erythroid derived 2, like 2 Mus musculus 150-154