PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 7856691-5 1995 The de novo secretion of monocyte chemotactic protein-1 in the culture supernatants was analyzed by immunoprecipitation and electrophoresis after metabolic labeling with sulfur 35-labeled cysteine. Cysteine 188-196 C-C motif chemokine ligand 2 Homo sapiens 25-55 10529171-10 1999 Additional constraints at the ends of the peptide, corresponding to the disulfide between the first and third cysteines in MCP-1, yielded further improvements in affinity. Cysteine 110-119 C-C motif chemokine ligand 2 Homo sapiens 123-128 9287323-5 1997 Mutation of highly conserved cysteines in the amino-terminal domain and third extracellular loop of CCR2, but not in the fusion protein, resulted in a dramatic loss of MCP-1 binding, suggesting the existence of a critical intramolecular disulfide bond that positions the amino-terminal protein for ligand interaction. Cysteine 29-38 C-C motif chemokine ligand 2 Homo sapiens 168-173 8989326-7 1997 Comparison of the three MCP-1 structures revealed a direct correlation between the main-chain conformation of the first two cysteine residues and the quaternary arrangements. Cysteine 124-132 C-C motif chemokine ligand 2 Homo sapiens 24-29 9225244-1 1996 The affinity-based N (alpha)-amino protecting group tetrabenzo[a,c,g,i]fluorenyl-17 methoxycarbonyl (Tbfmoc) has been utilized as a hydrophobic probe to allow the simple, quick and highly effective isolation of a 76 residue cysteine-containing protein (MCP-1). Cysteine 224-232 C-C motif chemokine ligand 2 Homo sapiens 253-258 28726203-2 2017 Migration of monocytes stimulated by cysteine-containing peptides (fragments of chemokines with free thiol group MCP-1 and fractalkine) was completely inhibited by apocinin and MEK/ERK blocker. Cysteine 37-45 C-C motif chemokine ligand 2 Homo sapiens 113-134 8290256-5 1994 Two mutations were identified in the p53 cDNA from HC11 cells: a missense mutation at codon 138, substituting Trp for Cys, and a microdeletion, codon 123 to 130, of exon 5. Cysteine 118-121 C-C motif chemokine ligand 2 Homo sapiens 51-55 1577716-4 1992 Edman degradation and mass spectrometry provided evidence that these protein-bound heme adducts were addition products in which heme-CCL2 or heme-CCl3 were bound to cysteine residue 93 of the beta-chain of hemoglobin. Cysteine 165-173 C-C motif chemokine ligand 2 Homo sapiens 133-137 33596158-0 2021 l-Cysteine Stimulates the Effect of Vitamin D on Inhibition of Oxidative Stress, IL-8, and MCP-1 Secretion in High Glucose Treated Monocytes. Cysteine 0-10 C-C motif chemokine ligand 2 Homo sapiens 91-96 33596158-3 2021 This study examined the hypothesis that supplementation with vitamin D, in combination with l-cysteine (LC), is better at reducing oxidative stress and thereby, more effective, at inhibiting the secretion of the pro-inflammatory cytokines, Interleukin-8 (IL-8) and monocyte chemoattractant protein-1 (MCP-1) in U937 monocytes exposed to high glucose concentrations. Cysteine 104-106 C-C motif chemokine ligand 2 Homo sapiens 265-299 33596158-3 2021 This study examined the hypothesis that supplementation with vitamin D, in combination with l-cysteine (LC), is better at reducing oxidative stress and thereby, more effective, at inhibiting the secretion of the pro-inflammatory cytokines, Interleukin-8 (IL-8) and monocyte chemoattractant protein-1 (MCP-1) in U937 monocytes exposed to high glucose concentrations. Cysteine 104-106 C-C motif chemokine ligand 2 Homo sapiens 301-306 21670067-5 2011 Nonreduced mCRP was largely inert in activating human coronary artery endothelial cells (HCAECs), whereas reduced or cysteine-mutated mCRP evoked marked release of IL-8 and monocyte chemoattractant protein-1 from HCAECs, with ~50% increase at a concentration of 1 mug/ml. Cysteine 117-125 C-C motif chemokine ligand 2 Homo sapiens 173-207 26050467-1 2015 Automated Fmoc solid-phase technique was used to synthesize Cys-containing linear peptide fragments of monocyte chemoattractant protein-1 and chemokine domain of fractalkine along with their analogues with Cys residue being either modified or replaced with Ser. Cysteine 60-63 C-C motif chemokine ligand 2 Homo sapiens 103-137 20092409-3 2010 We further observed that supplementation with H(2)S or an endogenous precursor of H(2)S (l-cysteine) in culture medium prevents IL-8 and MCP-1 secretion in high-glucose-treated human U937 monocytes. Cysteine 89-99 C-C motif chemokine ligand 2 Homo sapiens 137-142