PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
10529171-10	1999	Additional constraints at the ends of the peptide, corresponding to the disulfide between the first and third cysteines in MCP-1, yielded further improvements in affinity.	Cysteine	110-119	C-C motif chemokine ligand 2	Homo sapiens	123-128	
28726203-2	2017	Migration of monocytes stimulated by cysteine-containing peptides (fragments of chemokines with free thiol group MCP-1 and fractalkine) was completely inhibited by apocinin and MEK/ERK blocker.	Cysteine	37-45	C-C motif chemokine ligand 2	Homo sapiens	113-134	
20092409-3	2010	We further observed that supplementation with H(2)S or an endogenous precursor of H(2)S (l-cysteine) in culture medium prevents IL-8 and MCP-1 secretion in high-glucose-treated human U937 monocytes.	Cysteine	89-99	C-C motif chemokine ligand 2	Homo sapiens	137-142	
26050467-1	2015	Automated Fmoc solid-phase technique was used to synthesize Cys-containing linear peptide fragments of monocyte chemoattractant protein-1 and chemokine domain of fractalkine along with their analogues with Cys residue being either modified or replaced with Ser.	Cysteine	60-63	C-C motif chemokine ligand 2	Homo sapiens	103-137	
21670067-5	2011	Nonreduced mCRP was largely inert in activating human coronary artery endothelial cells (HCAECs), whereas reduced or cysteine-mutated mCRP evoked marked release of IL-8 and monocyte chemoattractant protein-1 from HCAECs, with ~50% increase at a concentration of 1 mug/ml.	Cysteine	117-125	C-C motif chemokine ligand 2	Homo sapiens	173-207	
9287323-5	1997	Mutation of highly conserved cysteines in the amino-terminal domain and third extracellular loop of CCR2, but not in the fusion protein, resulted in a dramatic loss of MCP-1 binding, suggesting the existence of a critical intramolecular disulfide bond that positions the amino-terminal protein for ligand interaction.	Cysteine	29-38	C-C motif chemokine ligand 2	Homo sapiens	168-173	
8989326-7	1997	Comparison of the three MCP-1 structures revealed a direct correlation between the main-chain conformation of the first two cysteine residues and the quaternary arrangements.	Cysteine	124-132	C-C motif chemokine ligand 2	Homo sapiens	24-29	
9225244-1	1996	The affinity-based N (alpha)-amino protecting group tetrabenzo[a,c,g,i]fluorenyl-17 methoxycarbonyl (Tbfmoc) has been utilized as a hydrophobic probe to allow the simple, quick and highly effective isolation of a 76 residue cysteine-containing protein (MCP-1).	Cysteine	224-232	C-C motif chemokine ligand 2	Homo sapiens	253-258	
8290256-5	1994	Two mutations were identified in the p53 cDNA from HC11 cells: a missense mutation at codon 138, substituting Trp for Cys, and a microdeletion, codon 123 to 130, of exon 5.	Cysteine	118-121	C-C motif chemokine ligand 2	Homo sapiens	51-55	
7856691-5	1995	The de novo secretion of monocyte chemotactic protein-1 in the culture supernatants was analyzed by immunoprecipitation and electrophoresis after metabolic labeling with sulfur 35-labeled cysteine.	Cysteine	188-196	C-C motif chemokine ligand 2	Homo sapiens	25-55	
1577716-4	1992	Edman degradation and mass spectrometry provided evidence that these protein-bound heme adducts were addition products in which heme-CCL2 or heme-CCl3 were bound to cysteine residue 93 of the beta-chain of hemoglobin.	Cysteine	165-173	C-C motif chemokine ligand 2	Homo sapiens	133-137	
33596158-0	2021	l-Cysteine Stimulates the Effect of Vitamin D on Inhibition of Oxidative Stress, IL-8, and MCP-1 Secretion in High Glucose Treated Monocytes.	Cysteine	0-10	C-C motif chemokine ligand 2	Homo sapiens	91-96	
33596158-3	2021	This study examined the hypothesis that supplementation with vitamin D, in combination with l-cysteine (LC), is better at reducing oxidative stress and thereby, more effective, at inhibiting the secretion of the pro-inflammatory cytokines, Interleukin-8 (IL-8) and monocyte chemoattractant protein-1 (MCP-1) in U937 monocytes exposed to high glucose concentrations.	Cysteine	104-106	C-C motif chemokine ligand 2	Homo sapiens	265-299	
33596158-3	2021	This study examined the hypothesis that supplementation with vitamin D, in combination with l-cysteine (LC), is better at reducing oxidative stress and thereby, more effective, at inhibiting the secretion of the pro-inflammatory cytokines, Interleukin-8 (IL-8) and monocyte chemoattractant protein-1 (MCP-1) in U937 monocytes exposed to high glucose concentrations.	Cysteine	104-106	C-C motif chemokine ligand 2	Homo sapiens	301-306