PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 11936698-4 2002 Using the C1a gentamicin peak, linearity was demonstrated from 0.5 to 10 microg ml(-1) and the limit of detection was 75 microg l(-1). Gentamicins 14-24 endogenous retrovirus group K member 1 Homo sapiens 10-13 4091297-2 1985 The use of sisomicin, a structural analogue of a C1a gentamicin fraction, is an alternative to gentamicin therapy for economical reasons. Gentamicins 53-63 endogenous retrovirus group K member 1 Homo sapiens 49-52 34274343-1 2021 BACKGROUND: Total gentamicin is a sum of five congeners C1, C1a, C2, C2a and minor C2b, which differ from each other in their methylation on the purpurosamine ring. Gentamicins 18-28 endogenous retrovirus group K member 1 Homo sapiens 60-63 11401545-14 2001 Furthermore, comparison of enzyme-bound conformations of isepamicin to the RNA-bound conformation of gentamycin C1a also showed remarkable similarities between the enzyme-bound and RNA-bound aminoglycoside antibiotic conformations. Gentamicins 101-111 endogenous retrovirus group K member 1 Homo sapiens 112-115 6664082-4 1983 Gentamicin was separated into three major isomers (C1, C2, and C1a) on a reversed-phase octyl column by eluting with a mobile phase. Gentamicins 0-10 endogenous retrovirus group K member 1 Homo sapiens 63-66 27871844-3 2017 Total gentamicin is the sum of the concentrations of five known congeners C1, C1a, C2, C2a and C2b. Gentamicins 6-16 endogenous retrovirus group K member 1 Homo sapiens 78-81 6134794-3 1983 spectroscopy to the quantitative analysis of the C1, C1a, and C2 components of gentamicin sulphate samples are described. Gentamicins 79-98 endogenous retrovirus group K member 1 Homo sapiens 53-56 24708-1 1978 The proportions of the main components present in gentamicin sulphate complex, gentamicins C1, C1a and C2, can be monitored by 1H nuclear magnetic resonance (nmr) spectrometry. Gentamicins 50-69 endogenous retrovirus group K member 1 Homo sapiens 95-98 974239-1 1976 Gentamicin sulphate employed in therapeutics consists of a mixture of three major aminoglycoside components, the gentamicins C1, C1a and C2. Gentamicins 0-19 endogenous retrovirus group K member 1 Homo sapiens 129-132 7142334-0 1982 Determination of gentamicin components C1a, C2 and C1 in plasma and urine by high-performance liquid chromatography. Gentamicins 17-27 endogenous retrovirus group K member 1 Homo sapiens 39-42 32601158-3 2020 In gentamicin, four components, known as gentamicin congeners C1, C1a, C2, and C2a, comprise the majority of the mixture. Gentamicins 41-51 endogenous retrovirus group K member 1 Homo sapiens 66-69 21548130-3 2011 The HSCCC/ESI-MS peaks indicated that gentamicin C1a (m/z 450: [M+H](+)), C2/2a (m/z 464: [M+H](+)) and C1 (m/z 478: [M+H](+)) have the peak resolution values of 1.3 and 1.7 from 30 mg of loaded gentamicin powder. Gentamicins 38-48 endogenous retrovirus group K member 1 Homo sapiens 49-52 23460973-8 2012 One milligram of gentamycin C1a, C2, C2a and C1 was equal to 1 286.98, 1 095.74, 1 079.52 and 739.61 gentamycin units, respectively. Gentamicins 17-27 endogenous retrovirus group K member 1 Homo sapiens 28-31 23460973-8 2012 One milligram of gentamycin C1a, C2, C2a and C1 was equal to 1 286.98, 1 095.74, 1 079.52 and 739.61 gentamycin units, respectively. Gentamicins 101-111 endogenous retrovirus group K member 1 Homo sapiens 28-31 21839597-5 2011 The developed method for the determination of gentamicin provides complete base line separation of components C1, C1a, C2, C2a and C2b mentioned in the European and British Pharmacopoeias. Gentamicins 46-56 endogenous retrovirus group K member 1 Homo sapiens 114-117 21548130-7 2011 These gentamicin isomers of C1a, C2/2a and C1 were evaluated for their antibacterial activities. Gentamicins 6-16 endogenous retrovirus group K member 1 Homo sapiens 28-31 15058594-7 2004 This method allows the determination of the composition in components C1, C1a, C2, C2a and C2b of gentamicin sulfate samples. Gentamicins 98-116 endogenous retrovirus group K member 1 Homo sapiens 74-77 15690437-11 2005 This method for determination of gentamicin C1, C1a, C2a, and C2 in human serum can thus be used in the entire therapeutic concentrations range of gentamicin. Gentamicins 147-157 endogenous retrovirus group K member 1 Homo sapiens 48-51 15624170-3 2005 Under optimized separation conditions (0.2 mM cetyltrimethylammonium bromide (CTAB), 1 mM ammonium citrate, pH 3.5), gentamicin was separated into three major peaks (C1, C1a, and C2+C2a) within 15 min. Gentamicins 117-127 endogenous retrovirus group K member 1 Homo sapiens 170-173 14667706-1 2003 A simple method for the separation of the major components of commercial gentamicin sulfate (C-1, C-1a, C-2, C-2a) by high-performance liquid chromatography (HPLC) on an analytical and a semipreparative scale was developed. Gentamicins 73-91 endogenous retrovirus group K member 1 Homo sapiens 98-102